Evidence map›Paper›PMID 41064452›Full record

ReviewFrontiers in pharmacology2025

Research overview of ethnic medicines for the treatment of rheumatoid arthritis.

Xiao-Jing Lei, Hong-Mei Sun, Yun-Xia Qu, Qing-Zhu Xu, Ying Zhou, Huai Xiao, Li-Juan Li, Zhi-Bin Yang

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. GenusLife (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao-Jing LeiYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Hong-Mei SunYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Yun-Xia QuYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Qing-Zhu XuYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Ying ZhouYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Huai XiaoYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.
Li-Juan LiCollege of pharmacy, National-Local Joint Engineering Research Center of Entomoceutics, Dali, Yunnan, China.
Zhi-Bin YangYunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, College of Pharmacy, Dali University, Dali, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common clinical autoimmune disease, characterized by persistent synovitis, cartilage destruction and systemic complications, and the incidence of which is increasing every year. The current study found that the characteristics of multi-component, multi-target, and overall regulation of ethnic drugs have significant effects on the prevention and treatment of RA, with less toxicity and side effects. However, there is a lack of comprehensive overview of existing ethnic medicine treatments for RA. This paper summarizes the available ethnomedicines for RA and reviews the current status of research on ethnomedicines against RA, experimental and clinical studies on some common ethnomedicines for RA, and the effects of non-pharmacological treatments on RA. First of all, the search terms "Chinese medicine," "traditional Chinese medicine," "ethnomedicine," "arthritis," "rheumatoid arthritis," "Mongolian medicine," "Zhuang medicine," "Miao medicine" and "Tibetan medicine" were used as search terms to search for relevant literature using Pubmed, China National Knowledge Internet (CNKI) and Wanfang data (1996-2024); secondly, the missing basic information of ethnomedicine collected was supplemented using two databases, namely, Clinical Diagnosis and Treatment Knowledge Base and the Basic Information Base of Chinese Herbal Medicine-Yaozhi data. Among the national medicines for the treatment of RA, the Tibetan medicine, Miao medicine, Zhuang medicine, Mongolian medicine, Dai medicine and Hui medicine are mostly used in the majority of medicinal materials, and the research reports are also in the majority. Other national medicines are also available, but the medicinal materials used are less, the research reports are less, or even not. The treatment of RA, whether experimental or clinical research, is mainly based on compound prescriptions, less use of single herbs, and non-drug therapy. This may provide drug selection and insights for the future experimental and clinical research directions of ethnic drugs widely used in the treatment of RA. Nevertheless, there is still a need for more mechanism research and exploration, as well as pharmacological, toxicological and clinical research on existing or untapped ethnomedicines.

Indexed as

ethnic medicineethnomedicinereviewrheumatoid arthritis (RA)traditional Chinese medicine

Identifiers

PMID41064452
PMCPMC12500662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.