Evidence map›Paper›PMID 41064335›Full record

ArticleJournal of multidisciplinary healthcare2025

Mapping the Treatment Journey of Children on Subcutaneous House Dust Mite Immunotherapy: A Qualitative Study.

Shidi Xu, Zhujun Gu, Jie Zhao, Jiehua Xu, Jun Xie

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shidi Xu *Department of Respiratory Medicine, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, Jiangsu, People's Republic of China.
Zhujun Gu *Department of Respiratory Medicine, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, Jiangsu, People's Republic of China.
Jie ZhaoDepartment of Respiratory Medicine, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, Jiangsu, People's Republic of China.
Jiehua XuDepartment of Respiratory Medicine, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, Jiangsu, People's Republic of China.
Jun XieNursing Department, Affiliated Children's Hospital of Jiangnan University (Wuxi Children's Hospital), Wuxi, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although subcutaneous immunotherapy (SCIT) is a first-line treatment for the prevalent house dust mite allergy (affecting ~30% of children in humid regions), the longitudinal realities of managing this years-long therapy for children and their parents/carers are poorly documented. Methods: We conducted semi-structured interviews with 15 child-caregiver dyads (children aged 6-12 years) undergoing SCIT. Data were analyzed using framework analysis to map challenges across four treatment phases: diagnosis/screening, initiation, maintenance, and follow-up. Results: Key findings included: Diagnostic delays (mean 10.2 months) due to non-specific symptoms (86.7% morning sneezing). Injection anxiety (initial Visual Analog Scale (VAS): 7.8/10) improved with play-based interventions (64% reduction). School challenges: 64.2% faced symptom management difficulties; 57.1% experienced peer stigma. Economic burden: Annual direct costs averaged ¥8750 (US$1250). Conclusion: This study identifies modifiable gaps in SCIT delivery, advocating for: Early symptom recognition tools, Child-friendly anxiety-reduction protocols, and School-based support programs. The proposed "hospital-school-family" tripartite system may optimize outcomes globally.

Indexed as

health-related quality of lifemultidisciplinary carepatient journey mappingpediatric allergySCITsubcutaneous immunotherapytreatment adherence

Identifiers

PMID41064335
PMCPMC12500474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.