ArticleCase reports in dermatology
Needling as a Potential and Novel Treatment for Skin Ischemia following Filler-Induced Vascular Occlusion: A Case Series.
Article in Case reports in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dissolving Hyaluronic Acid Filler: The Diffusion Barrier to Hyaluronidase Efficacy.Journal of cosmetic dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The most severe complication of filler injection is ischemia due to vascular occlusion, causing skin necrosis, scarring, blindness, and even stroke. Among the available treatments, needling therapy has been used in some clinical practices but has been rarely studied and discussed. Case Presentations: Four recent skin ischemia cases with subsequent needling procedure were observed retrospectively and pertinent literature was analyzed. The objective was to evaluate the efficacy and safety of needling procedure for filler-induced skin ischemia, which is unresponsive to standard therapies. Conclusion: All of the 4 cases recovered from skin ischemia without side effects by receiving needling procedure. The available data demonstrate some potential mechanisms of needling, such as embolus releasing, ischemia reperfusion and revascularization. Although there is a lack of conclusive evidence for improving the hypoperfusion area by needling treatment, the current cases observation and theoretical analysis as well as our cases provide evidence supporting its potential as an efficacious, simple, and secure treatment for vascular complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.