Evidence map›Paper›PMID 41064290›Full record

ArticleFrontiers in nutrition2025

Xihua Yu, Gao Tian, Yi Wang, Liuruolan Li, Liming Huang, Yurong Zhao, Ling Feng, Yuhao Zhao, Haiqin Fang, Wenwei Lu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Intestinal-Bone Axis Mediated byMicroorganisms · 2026
    Review
  2. Article
  3. Frontiers in nutrition · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xihua YuSinopharm Xingsha Pharmaceutical (Xiamen) Co., Ltd., Xiamen, China.
Gao TianState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Yi WangSinopharm Xingsha Pharmaceutical (Xiamen) Co., Ltd., Xiamen, China.
Liuruolan LiSinopharm Xingsha Pharmaceutical (Xiamen) Co., Ltd., Xiamen, China.
Liming HuangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Yurong ZhaoState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Ling FengState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Yuhao ZhaoState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Haiqin FangNHC Key Laboratory of Food Safety Assessment, Chinese Academy of Medical Science Research Unit (2019RU014), China National Center for Food Safety Risk Assessment, Beijing, China.
Wenwei LuState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.
Shourong LuThe Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Hongchao WangState Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Elderly individuals exhibit heightened susceptibility to osteoporosis, largely attributable to age-related declines in skin, liver, and kidney function. While vitamin D (VD) supplementation is common, its efficacy is often limited, necessitating reliance on pharmaceutical interventions. Research indicates that the intestinal flora significantly influences intestinal VD metabolism, with probiotic supplementation demonstrably impacting circulating VD levels. Methods: We employed an fecal fermentation model to screen bacterial strains. After introducing these strains into osteoporotic mice, we tested the mice's serum and skeletal indicators. We then conducted a correlation analysis between the mice's key intestinal microbiota and serum and skeletal indicators. Results and discussion: We identify

Indexed as

active vitaminsintestinal floraosteoporosisprobioticsvitamin D

Identifiers

PMID41064290
PMCPMC12502076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.