ArticleHealth science reports2025
The Current Landscape of Pancreatic Cancer Management in Sub-Saharan Africa - A Perspective Review.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Clinical Presentation and Management Outcomes of Pancreatic Cancer in African Countries: A Scoping Review.Journal of gastrointestinal cancer · 2026Article
- The Joint Global Epidemiology of Pancreatic Cancer and Pancreatitis: Co-Occurrence Patterns, Shared Risk Factors, and Projections to 2040.United European gastroenterology journal · 2026Article
- Invasive Adenosquamous Carcinoma of the Pancreas: Two Case Reports From Tanzania and a Literature Review.Case reports in pathology · 2026Article
- The Current Landscape of Pancreatic Cancer Management in Sub-Saharan Africa - A Perspective Review.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Pancreatic cancer remains a significant public health challenge in Sub-Saharan Africa (SSA), with a high mortality-to-incidence ratio driven by late-stage diagnoses, limited therapeutic access, and systemic healthcare disparities. This perspective aims to synthesize current evidence on the epidemiology, diagnostic capacity, treatment options, and structural barriers contributing to poor outcomes, while highlighting opportunities for targeted interventions and policy reforms. Methods: We conducted a narrative review of peer-reviewed literature, regional reports, and epidemiological studies describing the burden and management of pancreatic cancer across SSA. Data were synthesized to characterize diagnostic pathways, surgical and palliative care practices, workforce capacity, and environmental risk factors. Strategies to address identified gaps were developed based on published evidence from similar resource-constrained settings. Results: Available data indicate that over 80% of patients in SSA present with advanced or metastatic disease. Diagnostic imaging, including CT and MRI, remains inaccessible in many regions, and biopsies are frequently obtained intraoperatively due to limited endoscopic capacity. Curative surgical resections are rare (< 10%), with palliative bypass procedures predominating. Chemotherapy and radiotherapy services are inconsistently available, and access to opioid analgesics remains below 50% in many centres. Contributing factors include underdeveloped infrastructure, insufficient specialized training, high out-of-pocket costs, and heavy metal environmental exposures. Conclusion: Improving pancreatic cancer outcomes in SSA requires a comprehensive, multi-sectoral response that prioritizes infrastructure investment, workforce training, and equitable access to diagnostics and therapies. Establishing regional cancer centres, expanding perioperative and palliative nursing roles, strengthening cancer registries, and enforcing environmental regulations are critical steps. Collaboration with international organizations and community stakeholders will be essential to develop context-specific guidelines and sustainable solutions that can reduce disease burden and improve survival rates in the region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.