Evidence map›Paper›PMID 41064149›Full record

ArticleRSC advances2025

Tuning i-motif folding and stability with acyclic phosphonate-linked (ZNA) cytidine residues.

Marlies Derden, Sten Reynders, Jérôme Rihon, Xinlu Li, Frédérick Coosemans, Jef Rozenski, Piet Herdewijn, Elisabetta Groaz, Eveline Lescrinier

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marlies DerdenKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Sten ReyndersKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Jérôme RihonKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Xinlu LiKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Frédérick CoosemansKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Jef RozenskiKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.
Piet HerdewijnKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.ORCID https://orcid.org/0000-0003-3589-8503
Elisabetta GroazKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.ORCID https://orcid.org/0000-0002-8866-2265
Eveline LescrinierKU Leuven, Rega Institute for Medical Research, Medicinal Chemistry Herestraat 49-Box 1041 3000 Leuven Belgium elisabetta.groaz@kuleuven.be eveline.lescrinier@kuleuven.be.ORCID https://orcid.org/0000-0001-7066-4329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

i-Motifs (iMs) are non-canonical four-stranded DNA structures stabilized by hemi-protonated (C:H

Identifiers

PMID41064149
PMCPMC12501961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.