ArticleFrontiers in oncology2025
Efficacy and safety of thoracic radiotherapy combined with anti-angiogenic therapy and immunochemotherapy for advanced non-small cell lung cancer patients: a retrospective study.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- A radiotherapy resistance-related prognostic signature predicts survival and the immune landscape in rectal cancer.Translational cancer research · 2026Article
- Integrated management of immunotherapy and radiotherapy for patients with metastatic non-small cell lung cancer: a narrative review of current landscape and future directions.Translational lung cancer research · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Purpose: To assess the efficacy and safety of radiotherapy combined with anti-angiogenic therapy, immune checkpoint inhibitors, and chemotherapy for advanced non-small cell lung cancer (NSCLC). Methods: Patients who have received at least two cycles of quadruple therapy were Progression-free survival (PFS), overall survival (OS), and treatment-related side effects were comprehensively evaluated using R language and the chi-square test. Results: Seventy-four patients were enrolled and divided into two groups (A and B) based on whether they had received radiotherapy. The incidence rate of adverse events-such as radiation-related pneumonitis, pneumonia, thrombocytopenia, cough, panting, fatigue, and radiodermatitis-were significantly higher in patients receiving radiotherapy. A survival analysis comparing the experimental and control groups revealed that the addition of radiotherapy played a positive role in extending PFS and OS, with statistically significant results observed for OS (HR(95%CI)=0.51[0.283, 0.919]; Conclusions: Sequential radiotherapy after quadruple therapy can prolong survival in patients with advanced NSCLC. However, special attention should be paid to treatment-related side effects such as pneumonitis, pneumonia, and thrombocytopenia, which may negatively affect prognosis.
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