Evidence map›Paper›PMID 41064078›Full record

ArticleFrontiers in oncology2025

Nomogram model for prognosis of early colorectal cancer after endoscopic therapy: integration of intestinal microbiota and clinicopathological parameters.

Yanli Zhu, Fang Yang, Lijun Meng, Xiaoling Zhang, Yongsheng Chang, Lanfang Zhang

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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Yanli ZhuDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.
Fang YangDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.
Lijun MengDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.
Xiaoling ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.
Yongsheng ChangDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.
Lanfang ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Henan Medical University, Xinxiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To integrate the characteristics of intestinal flora and clinical pathological parameters in patients with early colorectal cancer, and to construct and validate a nomogram model for predicting the prognosis of endoscopic therapy. Methods: The data of 80 patients with early colorectal cancer receiving endoscopic treatment from January 2019 to June 2024 were retrospectively collected. They were randomly divided into a training set (n = 56) and a validation set (n = 24) at a ratio of 7:3. The factors related to prognosis were screened by univariate analysis and multivariate Logistic regression analysis regression, so as to construct Nomogram model, calculate C-index, and draw the calibration curve. The clinical application value of the model was evaluated using decision curve analysis (DCA). Results: There was no significant difference in the incidence of poor prognosis, intestinal flora, and clinical pathological parameters between the training set and the validation set (all Conclusion: Nomogram model based on intestinal flora and clinical pathological parameters can effectively predict the prognosis of early colorectal cancer patients after endoscopic treatment with good accuracy and reliability, which is expected to provide an important reference for the development of clinical individualized treatment plan and guide the accurate treatment and management of patients.

Indexed as

clinical pathological parametersearly colorectal cancerintestinal floranomogram modelprognosis of endoscopic therapy

Identifiers

PMID41064078
PMCPMC12500634

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