Evidence map›Paper›PMID 41064062›Full record

ArticleFrontiers in genetics2025

Case Report: a family report of hereditary pancreatitis caused by SPINK1 and PRSS1 gene mutations.

Jing Xu, Ying Hu, Banghui Xiao, Juan He, Miao Zhang, Rui Wang, Nianchun Peng

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing XuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Ying HuDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Banghui XiaoDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Juan HeDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Miao ZhangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Rui WangDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Nianchun PengDepartment of Endocrinology and Metabolism, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary pancreatitis (HP) is a rare genetic disorder of the pancreas. We report a case of a 20-year-old woman presenting with classic features of lean diabetes mellitus, chronic diarrhea, and diabetic ketoacidosis but notably without abdominal pain. Imaging revealed pancreatic calcification. Genetic testing identified pathogenic compound mutations in SPINK1 (c.194+2T>C) and PRSS1 (c.623G>C), confirming a diagnosis of HP. Family screening showed her mother carried a homozygous

Indexed as

diabetes mellitushereditary pancreatitispancreatitisPRSS1 geneSPINK1 gene

Identifiers

PMID41064062
PMCPMC12501505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.