ArticleJournal of surgical case reports2025
Delayed-onset organizing pneumonia following perioperative COVID-19 after lobectomy.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Delayed-onset organizing pneumonia as a manifestation of post-acute coronavirus disease 2019 (COVID-19) syndrome has not been documented in the perioperative setting. Here, a 61-year-old man underwent left lower lobectomy complicated by persistent air leakage requiring seven pleurodesis procedures. He developed COVID-19 on postoperative Day 10 and initially recovered but was readmitted on Day 27 with fever and respiratory failure. Chest computed tomography revealed progressive consolidations with ground-glass opacities. Initial methylprednisolone pulse therapy showed limited response, necessitating a second course with cyclosporine A addition. The patient achieved substantial radiological improvement by postoperative Day 104. Based on the biphasic clinical course, distinctive radiological progression, and limited steroid response, delayed-onset organizing pneumonia secondary to post-acute COVID-19 syndrome was diagnosed. This case highlights the importance of extended monitoring in post-lung resection patients with COVID-19 to enable early recognition and prompt intervention of delayed pulmonary complications.
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