ArticleFrontiers in immunology2025
Association of salivary lactoferrin,
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Salivary Cortisone as a Potential Alternative to Cortisol in Periodontitis Severity Assessment.International journal of molecular sciences · 2026Article
- Recent advances in metal-organic frameworks for therapeutic applications in periodontitis.Frontiers in medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Periodontitis is a prevalent inflammatory disease characterized by a dysbiotic oral microbiome, particularly involving Methods: A cohort of patients with and without a history of periodontitis was analyzed. Salivary and subgingival biofilm samples were collected to detect Results: Patients with a history of periodontitis showed significantly higher salivary lactoferrin, cortisol and DHEA levels compared to controls, along with increased Discussion: Our findings suggest that elevated lactoferrin, DHEA and cortisol levels reflect both immune-inflammatory and stress-mediated pathways in periodontitis, and its association with the abundance of
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Registered trials
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