Evidence map›Paper›PMID 41063908›Full record

ArticleCureus2025

A Case Report of Impending Thyroid Storm and Pemphigoid Gestationis Complicating Complete Molar Pregnancy.

Yaw Abrefa Safo, Dorothy Sackey, Theophilus B Sabi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yaw Abrefa SafoObstetrics and Gynaecology, Tema General Hospital, Tema, GHA.
Dorothy SackeyPediatrics, Battor Catholic Hospital, Battor, GHA.
Theophilus B SabiObstetrics and Gynaecology, Princess of Wales Hospital, Bridgend, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational trophoblastic disease, very rarely, is complicated by thyroid storm and pemphigoid gestationis. Thyroid storm is related to human chorionic gonadotropin hormone levels produced in pregnancy, but is usually exaggerated in molar pregnancies. With thyroid storm presenting acutely with cardiovascular and gastrointestinal collapse and pemphigoid gestationis manifesting as an intense, blistering, pruritic dermatosis, it is critical to recognise early the signs and symptoms to avert complications from these rare phenomena. We present a 24-year-old female who was referred with amenorrhoea of three months' duration with persistent vomiting, diarrhoea, and palpitations. She spontaneously expelled huge vesicular moles and subsequently developed pemphigoid gestationis. Skin biopsy showed focal spongiosis with subepidermal bullae and an admixture of eosinophils and neutrophils extending deep into the dermis with associated hyperkeratosis as well as intraepidermal blood-filled bullae. She was managed by a multidisciplinary team with prompt action to prevent deterioration.

Indexed as

gestational trophoblastic diseasemolar pregnancypemphigoid gestationisskin diseasethyroid storm

Identifiers

PMID41063908
PMCPMC12503898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.