Evidence map›Paper›PMID 41063882›Full record

ArticleCureus2025

An Atypical Presentation of Takayasu Arteritis: Isolated Tinnitus Followed by Ectopic Pregnancy.

Maria Alsarayreh, Eyad Elfar, Rahaf Khames

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria AlsarayrehDermatology, Private Practice, Orlando, USA.
Eyad ElfarFamily Medicine, WinMed Health, Orlando, USA.
Rahaf KhamesMedicine, Alfaisal University College of Medicine, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takayasu arteritis (TA) is a chronic large-vessel vasculitis that may present with a broad spectrum of clinical manifestations, some of which are subtle or atypical. Otologic symptoms are not commonly emphasized in this context, yet in some cases, they may precede more overt systemic findings, as illustrated in this report. We report a case of a 41-year-old female whose initial symptom was bilateral pulsatile tinnitus, occurring in the absence of hearing loss or audiometric abnormalities. In this patient, the tinnitus persisted for approximately five or six months before the onset of systemic complaints. Serial imaging over time revealed progressive, multi-territorial vascular involvement consistent with TA. Her treatment course included long-term corticosteroid therapy, which was complicated by an ectopic pregnancy requiring coordinated interdisciplinary care. This case highlights the potential relevance of isolated otologic symptoms as an early clinical clue in systemic vasculitis. Such atypical presentations can make the diagnosis more challenging and contribute to delays in treatment. It also underscores the importance of comprehensive management, including reproductive counseling for women of childbearing age and ongoing surveillance.

Indexed as

autoimmune vasculitisectopichearing losspregnancypregnancy complicationstakayasu arteritistinnitus

Identifiers

PMID41063882
PMCPMC12500480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.