Evidence map›Paper›PMID 41063861›Full record

ArticleCase reports in oncology

Urinary Stricture due to Localized Urethral AL Amyloidosis: A Case Report and Literature Review.

Marialaina Carter, Samuel Hall, Rosetta Campbell, Omar Alkharabsheh, Nabin R Karki

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PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Marialaina CarterDepartment of Internal Medicine, University of South Alabama, Mobile, AL, USA.
Samuel HallDivision of Medical Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA.
Rosetta CampbellDepartment of Pathology, University of South Alabama, Mobile, AL, USA.
Omar AlkharabshehDivision of Medical Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA.
Nabin R KarkiDivision of Medical Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The deposition of amyloid fibrils in various organs is a hallmark of amyloidosis, which is rarely isolated to a single site. We present a case of localized AL amyloidosis in a 23-year-old male who presented with hematuria from urethral stricture. Biopsy during urethroplasty confirmed amyloid deposition, and liquid chromatography-mass spectrometry identified the AL subtype. Case Presentation: A comprehensive workup, including bone marrow biopsy, fat pad biopsy, cardiac workup, and serum protein electrophoresis, excluded monoclonal disorder as well as widespread amyloid involvement. The patient underwent a two-stage urethroplasty and no evidence of recurrence locally or systemically during follow-up. Conclusion: This case emphasizes the importance of considering urethral amyloidosis in the differential diagnosis of urethral strictures, amyloid typing, and workup to excluding systemic involvement. True localized AL amyloidosis does not need amyloid-directed therapy initially but warrants close monitoring.

Indexed as

ALLight chain amyloidosisLocalized amyloidosisUrethral amyloidosisUrethral stricture

Identifiers

PMID41063861
PMCPMC12503635

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