ArticleFrontiers in global women's health2025
Risk factors for first-trimester spontaneous abortion and the role of preconception care.
Article in Frontiers in global women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Safety profile following mRNA-1273 COVID-19 primary vaccination in healthy adults in Indonesia.Global epidemiology · 2026Article
- Donidalorsen for the Treatment of Hereditary Angioedema: A Review of Clinical Studies.Drug design, development and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Spontaneous abortion in the first trimester is a common adverse pregnancy outcome with significant implications for maternal health and public health practice. The description of associations with modifiable factors, including preconception care, can aid in planning strategies to improve pregnancy outcomes. Methods: A retrospective analysis was conducted using data from 1,526 women, divided into two groups based on pregnancy outcomes: spontaneous abortion in the first trimester and live births. Binary and multivariate logistic regression analyses were performed to identify associations between factors (including preconception care) and the risk of spontaneous abortion in the first trimester. Results: Age >35 years [[OR] = 2.02, 95% [CI] = 1.49-2.75], obesity [[OR] = 1.81, 95% [CI] = 1.12-2.91], and a history of spontaneous abortion [[OR] = 1.57, 95% [CI] = 1.01-2.43] were associated with higher odds of spontaneous abortion in the first trimester, whereas preconception care was associated with lower odds of spontaneous abortion in the first trimester [[OR] = 0.58, 95% [CI] = 0.45-0.75]. Conclusion: The findings may help clinicians stratify pregnant women who require additional monitoring and pre-pregnancy interventions. From a public health perspective, integrating preconception care into routine health services can enhance maternal and neonatal outcomes, reduce healthcare costs, and improve health equity by targeting vulnerable populations. However, the results should be interpreted as associations, and prospective studies are needed to assess the potential effects of preconception care on spontaneous abortion in the first trimester.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.