Evidence map›Paper›PMID 41063792›Full record

ArticleRSC medicinal chemistry2025

Tanshinones target drug-resistant tuberculosis: efficacy, selectivity, and potential mechanism of action.

Giulia Polinário, Maiara A B C Rosa, Débora L Campos, Liliana L S Moraes, Marli M A de Campos, Ingrid Gracielle M Silva, Karine B Barros-Cordeiro, Sônia N Báo, Fernando R Pavan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giulia PolinárioTuberculosis Research Laboratory, School of Pharmaceutical Sciences, São Paulo State University - UNESP Araraquara São Paulo Brazil fernando.pavan@unesp.br.
Maiara A B C RosaTuberculosis Research Laboratory, School of Pharmaceutical Sciences, São Paulo State University - UNESP Araraquara São Paulo Brazil fernando.pavan@unesp.br.
Débora L CamposTuberculosis Research Laboratory, School of Pharmaceutical Sciences, São Paulo State University - UNESP Araraquara São Paulo Brazil fernando.pavan@unesp.br.
Liliana L S MoraesDepartment of Clinical and Toxicological Analysis, Federal University of Santa Maria (UFSM) Santa Maria RS Brazil.
Marli M A de CamposDepartment of Clinical and Toxicological Analysis, Federal University of Santa Maria (UFSM) Santa Maria RS Brazil.
Ingrid Gracielle M SilvaMicroscopy and Microanalysis Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasília Brasília DF Brazil.
Karine B Barros-CordeiroMicroscopy and Microanalysis Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasília Brasília DF Brazil.
Sônia N BáoMicroscopy and Microanalysis Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasília Brasília DF Brazil.
Fernando R PavanTuberculosis Research Laboratory, School of Pharmaceutical Sciences, São Paulo State University - UNESP Araraquara São Paulo Brazil fernando.pavan@unesp.br.ORCID https://orcid.org/0000-0002-6969-3963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the antimycobacterial potential of tanshinone I (TI), tanshinone IIA (TIIA), and cryptotanshinone (CPT), natural compounds isolated from

Identifiers

PMID41063792
PMCPMC12503125

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.