ArticleRespirology case reports2025
Pulmonary Dissemination in Adult-Onset Recurrent Respiratory Papillomatosis: A Rare and Severe Manifestation.
Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Pulmonary Dissemination in Adult-Onset Recurrent Respiratory Papillomatosis: A Rare and Severe Manifestation.Respirology case reports · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recurrent respiratory papillomatosis (RRP) commonly affects the upper airways, and lung parenchymal involvement is extremely rare. We present a case of adult-onset laryngotracheal RRP with lung parenchymal involvement that progressed despite systemic bevacizumab and ultimately required a left lower lobectomy. Histological features were characteristic of a squamous papilloma. Unusually, parenchymal involvement was present, with solid intra-alveolar nests cradled by preserved alveolar septa. Cytologic atypia and keratinisation were present; however, the absence of stromal desmoplasia and invasion precluded a diagnosis of squamous cell carcinoma and made overall classification challenging in this case. This case highlights the complexity of managing RRP with pulmonary involvement, particularly when disease progression persists despite systemic therapy such as systemic bevacizumab.
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