Evidence map›Paper›PMID 41063788›Full record

ArticleRespirology case reports2025

Unmasking Upper Airway Obstruction: A Case of Tracheobronchial Amyloidosis.

Abhir Nainani, Chui Lyn Leong, Vishnu Jeganathan, Siven Seevanayagam, Nicole Goh, Celia Lanteri

Erratum issuedAbstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Abhir NainaniAustin Health Respiratory and Sleep Medicine Melbourne Australia.
Chui Lyn LeongAustin Health Respiratory and Sleep Medicine Melbourne Australia.ORCID https://orcid.org/0000-0002-8602-5924
Vishnu JeganathanBendigo Health Respiratory Unit Bendigo Australia.
Siven SeevanayagamAustin Health Thoracic Surgery Melbourne Australia.
Nicole GohAustin Health Respiratory and Sleep Medicine Melbourne Australia.
Celia LanteriAustin Health Respiratory and Sleep Medicine Melbourne Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a rare case of a 76-year-old woman with severe tracheobronchial amyloidosis (TBA) causing airway collapse, in which the predominant underlying mechanism was expiratory central airway collapse (ECAC) secondary to both TBA and severe obstructive sleep apnoea (OSA). CPAP therapy effectively treated severe OSA, which likely contributed to a reduction in ECAC severity and alleviation of breathlessness. This case suggests that positive airway pressure ventilation may represent a valuable adjunctive treatment in patients with TBA exhibiting features of OSA, particularly when endobronchial intervention is contraindicated or not feasible.

Indexed as

positive airway pressuretracheobronchial amyloidosisupper airway obstruction

Identifiers

PMID41063788
PMCPMC12501491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.