Evidence map›Paper›PMID 41063764›Full record

ReviewBreast care (Basel, Switzerland)2026

New Perspectives in the Management of Triple-Negative Breast Cancer.

Rupert Bartsch, Zsuzsanna Bago-Horvath, Daniel Egle, Simon P Gampenrieder, Birgit Grünberger, Sonja Heibl, Maximilian Marhold, Caroline Preuss, Gabriel Rinnerthaler, Kathrin Strasser-Weippl and 3 more

Abstract readReview
In one paragraph

Review in Breast care (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A Pyrone Glucoside fromBiomolecules · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rupert BartschDepartment of Medicine 1, Division of Oncology, Medical University of Vienna, Vienna, Austria.
Zsuzsanna Bago-HorvathAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Daniel EgleAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Simon P GampenriederDepartment of Internal Medicine III with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Salzburg Cancer Research Institute - Laboratory for Immunological and Molecular Cancer Research (SCRI-LIMCR), Paracelsus Medical University Salzburg, Salzburg, Austria.
Birgit GrünbergerKlinische Abteilung für Innere Medizin III, Hämatologie und internistische Onkologie, Universitäts-Klinikum Wiener Neustadt, Wiener Neustadt, Austria.
Sonja HeiblAbteilung für Innere Medizin IV (Hämatologie, Internistische Onkologie und Palliativmedizin, Nephrologie und Dialyse), Klinikum Wels-Grieskirchen, Wels, Austria.
Maximilian MarholdDepartment of Medicine 1, Division of Oncology, Medical University of Vienna, Vienna, Austria.
Caroline PreussDepartment of Gynaecology, Obstetrics and Gynaecologic Endocrinology, Kepler University Hospital, Johannes Kepler University Linz, Linz, Austria.
Gabriel RinnerthalerAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Kathrin Strasser-WeipplZentrum für Onkologie und Hämatologie, Klinik Ottakring, Vienna, Austria.
Christoph SuppanAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Christian F SingerAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Michael GnantAustrian Breast and Colorectal Cancer Study Group, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The biological heterogeneity of triple-negative breast cancer (TNBC) and the availability of a growing number of therapeutic options necessitate continuous redefinition of the ideal treatment algorithm for patients with TNBC. Austrian experts convened for an advisory board meeting in November 2024 to discuss standards of care in the early and metastatic settings with a focus on the healthcare situation in Austria. Summary: This paper discusses biological principles, (neo)adjuvant treatment standards and strategies of escalation and de-escalation, as well as standards of care, new treatment options, and the management of central nervous system (CNS) disease in the setting of metastatic TNBC. Key Messages: TNBC remains a high-risk subtype of breast cancer. Neoadjuvant chemotherapy is preferred in early-stage disease starting from cT1c, cN0, with the addition of pembrolizumab recommended from clinical stage II. Post-neoadjuvant treatment is guided by the pathological response and

Indexed as

DiagnosisTreatmentTriple-negative breast cancer recommendations

Identifiers

PMID41063764
PMCPMC12503879

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.