Evidence map›Paper›PMID 41063727›Full record

ArticleRoyal Society open science2025

The neuro-immune crosstalk between periphery and central nervous system during acute immune response to virus-mimicking RNA in parrots.

Balraj Melepat, Daniel Divín, Kateřina Marková, Tao Li, Nithya Kuttiyarthu Veetil, Eleni Voukali, Lucie Schmiedová, Martin Těšický, Michal Vinkler

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Balraj MelepatDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0002-1830-9124
Daniel DivínDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0001-8513-7214
Kateřina MarkováDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0009-0009-1397-6516
Tao LiDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0002-3133-6194
Nithya Kuttiyarthu VeetilDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0002-1202-4902
Eleni VoukaliDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0001-6029-6171
Lucie SchmiedováDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0003-2180-5281
Martin TěšickýDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0001-8097-5331
Michal VinklerDepartment of Zoology, Faculty of Science, Charles University, Praha, Czech Republic.ORCID https://orcid.org/0000-0003-3572-9494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parrots, valued companion animals with a concerning conservation status, can act as reservoirs for zoonotic diseases. During various infections, systemic inflammation significantly impairs host health. However, the regulation of inflammatory responses in birds, particularly in cognitively advanced parrots, remains poorly understood. Here, we examine parrot systemic inflammation in response to virus-mimicking stimulation. In budgerigars (

Indexed as

avian immunologycytokine signallinggastrointestinal tractneural inflammationneuro-immune regulationneuroimmunology

Identifiers

PMID41063727
PMCPMC12503942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.