Evidence map›Paper›PMID 41063319›Full record

Trial reportEuropean journal of medical research2025

Preventive and therapeutic effects of semiconductor laser on pain in root canal treatment.

Ye Jian

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ye JianWuxi Stomatological Hospital, Special Needs Clinic, Wuxi, 214000, China. yjfly_smile@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the preventive and therapeutic effects of semiconductor laser on postoperative pain in root canal treatment and to compare the clinical efficacy of different laser application methods.

methodsA total of 202 patients requiring root canal treatment at our hospital's dental department from January to December 2024 were selected and randomly divided into experimental and Control groups using a random number table. The Control group received conventional root canal treatment (58 cases); the experimental group received 810 nm semiconductor laser-assisted treatment based on conventional root canal therapy and was further divided into three subgroups according to different laser application methods: laser-activated irrigation group (LAI group, 48 cases), low-level laser therapy group (LLLT group, 48 cases), and combined application group (Combined group, 48 cases). The LAI group used laser as a root canal irrigation activation system; the LLLT group applied laser irradiation to the buccal and palatal mucosa externally; the Combined group applied both methods simultaneously. All patients received root canal treatment completed in a single visit, and 197 patients completed the 14-day follow-up. Visual Analogue Scale (VAS) was used to assess the patients' pain levels at 1, 2, 3, 7, and 14 days after the procedure, and the use of analgesics was recorded.

resultsWithin 14 days after treatment, there were statistically significant differences in the mean VAS scores among the four groups (P < 0.05). The Control group had the highest pain scores, while the Combined group had the lowest. On the first day after treatment, the VAS scores of all experimental subgroups were significantly lower than the Control group (P < 0.001), with the LLLT group showing the best immediate pain relief effect. On days 2-3 after treatment, there was no significant difference in pain scores between the LAI and LLLT groups, but both were better than the Control group (P < 0.001). On day 7 after treatment, the Combined group had the most long-lasting analgesic effect, showing a significant difference compared to the Control group. By day 14, the differences among groups were no longer statistically significant (P > 0.05). Regarding analgesic use, the experimental groups required significantly less medication than the Control group (P < 0.001), with the Combined group using the least (0.53 ± 0.74 tablets). Moreover, multivariate analysis found that the size of periapical lesions, preoperative pain level, and laser treatment protocol were the main factors affecting postoperative pain.

conclusionSemiconductor laser can effectively reduce postoperative pain after root canal treatment and improve patient comfort. The combined application of laser-activated irrigation and low-level laser therapy techniques is the optimal pain prevention and control protocol, which can continuously provide analgesic effects for 14 days after treatment. As an adjunctive treatment, semiconductor laser effectively reduces discomfort in root canal treatment by enhancing root canal disinfection and promoting inflammatory tissue repair. This study provides scientific evidence for the rational application of semiconductor laser in clinical root canal treatment, which is of great significance for improving the success rate and patient satisfaction of root canal treatment.

Indexed as

Lasers, SemiconductorLow-Level Light TherapyPostoperative PainRoot Canal TherapyAdultFemaleHumansMaleMiddle AgedPain MeasurementTreatment OutcomeLaser-activated irrigationLow-level laser therapyPostoperative painPreventive and therapeutic effectsRoot canal treatmentSemiconductor laser

Identifiers

PMID41063319
PMCPMC12506317

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.