ArticleJournal of orthopaedic surgery and research2025
Association of different pain patterns with physical function in participants with knee osteoarthritis: data from the osteoarthritis initiative.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Predictors of Functional Recovery in Individuals Exposed to Late-Stage Exercise Programs After Total Knee Replacement: A Secondary Analysis of a Randomized Controlled Trial.Physical therapy · 2026Trial
- Central adiposity is associated with poorer functional capacity in women with knee osteoarthritis: a cross-sectional study with exploratory adjustment for pain intensity and radiographic severity.Rheumatology international · 2026Article
- Osteoarthritis as a systemic disorder: multi-organ crosstalk in pathogenesis and therapeutic targeting.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundPain is a multidimensional experience and a key symptoms of knee osteoarthritis (KOA). However, it remains unknown whether there is a specific pain pattern that is more strongly associated with physical function compared to other pain patterns among individuals with KOA. This study aimed to compare the correlations between different pain patterns and physical function, and identify the most related pain pattern with physical function in KOA.
methods412 participants with radiological KOA were included from the Osteoarthritis Initiative (OAI). Pain severity and four pain patterns were assessed, including intermittent, constant, weight-bearing, and non-weight-bearing pain patterns. Physical function was evaluated by the Western Ontario and McMaster Universities Arthritis Index physical function subscale (WOMAC-PF), Knee Injury and Osteoarthritis Outcome Score Function in Sport and Recreation (KOOS-FSR), 20-Meter Walking Test (20-MWT) and Repeated Chair Stand test (RCS).
resultsAmong pain severity and all pain patterns, the weight-bearing pain pattern had the strongest correlation with WOMAC-PF, and showed significant correlations with both WOMAC-PF and KOOS-FSR at baseline, year-2 follow up, and 2-year change (p < 0.001). All pain patterns and pain severity showed weakly significant correlation with 20-MWT and RCS.
conclusionsWeight-bearing pain pattern was most closely associated with self-reported physical function. Therapeutic targets related to weight-bearing pain should be preferred when administering analgesic therapies to improve physical function in KOA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.