ArticleBMC complementary medicine and therapies2025
Exploring antioxidant properties and antidiabetic potential of ten underutilized Sri Lankan fruits.
Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundManaging and treating diabetes mellitus is one of the scientific community's biggest challenges. This study aimed to determine phytochemicals, antioxidants, and antidiabetic properties of different solvent extracts of fruit plants as a source of natural products.
methodsThe total flavonoid content (TFC) and total phenolic content (TPC) were determined using standard methods. Antioxidant activities were determined using in vitro ferric reducing power (FRAP), oxygen radical absorbance capacity (ORAC), DPPH radical scavenging, and ABTS radical scavenging assay methods. The antidiabetic activities of the fruit extract were assessed using in vitro anti-amylase,anti-glucosidase , and anti-glycation assays.
resultsAmong different fractions of crude (CR), hexane (HX), ethyl acetate (EA), and aqueous (AQ), the highest TPC and TFC values were found in the HX fraction and EA fraction of Garcinia xanthochymus, respectively. The highest FRAP, ORAC, DPPH, and ABTS activities were found in the CR extract of G. xanthochymus, EA of G. xanthochymus, EA of Flacourtia indica, and HX fraction of G. xanthochymus, respectively. The highest anti-amylase inhibition was found in EA of G. xanthochymus, EA fraction of Careya arborea, and HX fraction of Syzygium zeylanicum compared to the standard drug Acarbose. The highest anti-glucosidase enzyme activities were found in the EA fraction of Elaeocarpus angustifolia, followed by the EA fraction of Cynometra cauliflora, the EA fraction of S. zeylanicum, the CR extract of F. indica, the AQ fraction of C. cauliflora, the EA fraction of C. arborea, the EA fraction of G. xanthochymus, the CR extract of C. cauliflora, and the CR extract of E. angustifolia compared to Acarbose. Antiglycation activities were higher in the HX fraction of S. zeylanicum, the EA fraction of G. xanthochymus, and C. arborea than in Rutin. None of the extracts showed inhibition for human salivary α-amylase enzyme.
conclusionThe ethyl acetate (EA) fractions of G. xanthochymus and C. arborea, along with the hexane (HX) fraction of S. zeylanicum, exhibited strong in vitro antioxidant and antidiabetic activities. These results indicate their potential as promising therapeutic candidates for the management of diabetes mellitus. However, further in vivo investigations are warranted to elucidate their mechanisms of action and assess their clinical applicability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.