Fatal recurrent Guillain-Barré syndrome (GBS) in an Ethiopian male: a case report.

Eden Tesfaye Beyene, Yonas Berhane Tesfay, Yared Getachew Tadesse, Estifanos Bekele Fole

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Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Eden Tesfaye BeyeneDepartment of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. dntsfy@gmail.com.ORCID http://orcid.org/0009-0005-0955-2519

Yonas Berhane TesfayDepartment of Internal Medicine, College of Health Sciences, Mekelle University, Tigray, Ethiopia.

Yared Getachew TadesseDepartment of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Estifanos Bekele FoleDepartment of Neurology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

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6 · The paper itself

Abstract

introductionGuillain-Barré syndrome (GBS) is a disease affecting the peripheral nerves, leading to a constellation of motor, sensory, and autonomic symptoms. It typically has a monophasic course, and recurrence is the exception rather than the case, so much is not known about it. We discuss the risk factors, presentation, and course of patients with recurrent Guillain-Barré syndrome. CASE PRESENTATION: A 28-year-old Ethiopian male presented with progressive ascending weakness that started from the lower extremities but spread to involve his respiratory muscles and resulted in respiratory failure. He had a similar but milder presentation 3 years prior and achieved a complete recovery. He was admitted to the intensive care unit where he passed away after 4 days.

conclusionGuillain-Barré syndrome can recur after years of complete recovery, and subsequent episodes tend to be more severe than the initial attack. Young age and lack of comorbidities are not determinants of clinical outcome in patients with recurrent Guillain-Barré syndrome.

Indexed as

Guillain-Barre SyndromeRespiratory InsufficiencyAdultEthiopiaFatal OutcomeHumansMaleMuscle WeaknessRecurrenceCase reportEthiopianFatal recurrenceGuillain–Barré syndrome

Identifiers

PMID41063185

DOI10.1186/s13256-025-05508-4

PMCPMC12505860

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