Evidence map›Paper›PMID 41063168›Full record

ArticleBMC oral health2025

Effectiveness of a new irrigation solution -RISA- on removing calcium hydroxide from artificial standardized grooves in root canals - an in vitro study.

İpek Eraslan Akyüz, Salih Düzgün, Hüseyin Sinan Topçuoğlu

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

İpek Eraslan AkyüzDepartment of Endodontics, Faculty of Dentistry, Erciyes University, Melikgazi, Kayseri, 38039, Turkey. ipekemamak@hotmail.com.ORCID http://orcid.org/0009-0004-0963-9617
Salih DüzgünDepartment of Endodontics, Faculty of Dentistry, Erciyes University, Melikgazi, Kayseri, 38039, Turkey.ORCID http://orcid.org/0000-0002-0868-3390
Hüseyin Sinan TopçuoğluDepartment of Endodontics, Faculty of Dentistry, Erciyes University, Melikgazi, Kayseri, 38039, Turkey.ORCID http://orcid.org/0000-0002-2581-7127

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEffective removal of intracanal drugs such as calcium hydroxide is important for the success of endodontic treatment and to prevent possible complications. This study aimed to evaluate the effect of modified salt solution (RISA), a new irrigation solution, in removing calcium hydroxide from artificial grooves in straight root canals.

methodsThe root canals of 60 human maxillary central incisors were prepared using Reciproc R40 files (VDW) up to size 40/0.04, rinsed with 2 mL of 2.5% NaOCl after each pecking motion, and then the teeth were split longitudinally. A lateral groove in the apical part was prepared in each root half and filled with calcium hydroxide, the root halves were reassembled and samples were placed in Eppendorf tubes. Three groups were established according to the irrigation solutions: group 1, Etilendiamintetraacetic acid (EDTA); group 2, RISA; group 3, Citric acid. After the root canals were irrigated with the irrigation solutions in each group, irrigation activation was performed with the Ultra X ultrasonic device (1 min). The samples were removed from the Eppendorf tubes, divided into two halves, and examined under a 24× magnification microscope by the two evaluators. Statistical analysis was performed using IBM SPSS version 23. Fisher Freeman Halton Test was used to analyze categorical data (p < 0.05).

resultsThere is no statistically significant difference between the score values ​​of the groups (p = 0.632).

conclusionsRISA solution was similarly effective in removing calcium hydroxide compared to EDTA and citric acid solutions in the apical region.

Indexed as

Calcium HydroxideDental Pulp CavityRoot Canal Filling MaterialsRoot Canal IrrigantsRoot Canal PreparationCitric AcidEdetic AcidHumansIncisorMaterials TestingSodium HypochloriteCalcium HydroxideCitric AcidEdetic AcidRoot Canal Filling MaterialsRoot Canal IrrigantsSodium HypochloriteArtificial grooveIntracanal medicamentIrrigation solutionUltrasonic activation

Identifiers

PMID41063168
PMCPMC12505819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.