ArticleVirology journal2025
Clinical and epidemiological characteristics of human metapneumovirus in children in Hangzhou, China.
Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Complete Blood Count-Derived Inflammatory Markers in Pediatric Lower Respiratory Tract Infection: A Narrative Review.Pathogens (Basel, Switzerland) · 2026Review
- Epidemiological Characteristics and Evolutionary Characterization of Human Metapneumovirus in Jiaxing, China.Viruses · 2026Article
- Development and Validation of a Nomogram for Predicting Severe Respiratory Illness in Children with Isolated Human Metapneumovirus Infection.Children (Basel, Switzerland) · 2026Article
- Epidemiological and Molecular Characterization of Human Metapneumovirus (HMPV) in Children Under 14 Years of Age in Shijiazhuang City, China.Pathogens (Basel, Switzerland) · 2026Article
- Epidemiology, bacterial coinfection risk factors, and inflammatory markers in children with RSV, AdV, and hMPV pneumonia in Zunyi, China.BMC infectious diseases · 2026Article
- Epidemiological characterization and phylogenetic analysis of human metapneumovirus isolated from children in Ningbo, China, 2020-2024.Microbial genomics · 2026Article
- Associations of age, comorbidities, and inflammatory markers with disease severity in pediatric human metapneumovirus infection.European journal of pediatrics · 2026Article
- Clinical Outcomes and Molecular Epidemiology of Human Metapneumovirus in Romanian Hospitalized Patients.Microorganisms · 2026Article
- Clinical characteristics and risk factors for severe community-acquired pneumonia in hospitalized children with human metapneumovirus infection in Shanghai: a retrospective cohort study.Frontiers in medicine · 2026Article
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9 authors.
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Abstract
This study aims to describe the epidemiology and genotypic diversity of human metapneumovirus (HMPV) in hospitalized children with pneumonia in Hangzhou, Zhejiang, China. From February 2022 to January 2023, nasopharyngeal swabs from hospitalized children with acute respiratory tract infections (ARTIs) in the Children's Hospital, Zhejiang University School of Medicine (Zhejiang, Hangzhou) were collected and tested for HMPV. Clinical characteristics and genotypes were analyzed on HMPV-positive samples. 3.43% (357/12993) of pediatric patients were HMPV-positive, and 287 of them were hospitalized with HMPV-induced pneumonia. 185 were classified as non-severe pneumonia group, and 102 as severe pneumonia group. Neutrophil to lymphocyte ratio (NLR), C-reactive protein to prealbumin ratio (CPAR) and C-reactive protein (CRP) were substantially higher in severe groups compared to non-severe groups across all patient categories (P < 0.05). There were 14 cases of B1 lineage infection, 7 cases of B2 lineage infection and 105 cases of A2.2.2 lineage infection in hospitalized patients. Under the prevention and control of the COVID-19 pandemic, the HMPV infection rate in pediatric patients with ARTIs has decreased, and the main lineage of HMPV infection in Hangzhou was A2.2.2. NLR and CPAR have higher predictive potential in severe patients.
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