ArticleBMC psychiatry2025
Nocturnal hypoxia moderates the relationship between rapid eye movement sleep and anxiety.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Higher Prevalence of Cognitive Impairment in Residents of High-Altitude Regions.Oxygen (Basel, Switzerland) · 2026Article
- Reduced Slow-Wave Sleep and Sleep-Disordered Breathing Are Linked to Suicidal Ideation in Major Depressive Disorder.Brain and behavior · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
objectiveSleep problems, especially rapid eye movement sleep disturbances, are associated with various neurological and psychological disorders. Given the potential of nocturnal hypoxia to induce psychological symptoms, we investigated its moderating effect on the relationship between sleep variables and psychological symptoms among individuals with sleep disturbances.
methodsA total of 160 participants who complained of sleep problems were enrolled, and their hypoxic and sleep indices were recorded using overnight polysomnography. The psychological status of all participants was further assessed using Symptom Checklist-90-R (SCL-90-R, Chinese version). Hierarchical regression analyses were employed to examine the influence of hypoxic indices and sleep indices, and the interaction of these variables on psychological symptoms. Simple slope analyses were used to probe significant interactions.
resultsHierarchical regression analyses indicated that the cumulative duration of nocturnal hypoxia (SpO
conclusionOur study demonstrates that nocturnal hypoxia, particularly the cumulative duration of hypoxia (SpO
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