Evidence map›Paper›PMID 41063055›Full record

ArticleBMC musculoskeletal disorders2025

Arthroscopic repair of the anterior talofibular ligament with retrograde drilling and allograft bone grafting for chronic lateral ankle instability with hepple stage V osteochondral lesions of the talus.

Shu Chen, Yaguang Han, Lei Zhang, Jinhui Peng, Shuai Yuan, Haobo Li, Qirong Qian, Jun Zhu, Yiqin Zhou

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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Shu Chen *Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Yaguang Han *Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Lei Zhang *Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Jinhui PengDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Shuai YuanDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Haobo LiDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China.
Qirong QianDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China. qianqr@163.com.
Jun ZhuDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China. arthrozhujun@sina.com.
Yiqin ZhouDepartment of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Feng yang Road, 200003, Shanghai, People's Republic of China. drzhouyiqin@163.com.

Funding

National Natural Science Foundation of China 82272471
6 · The paper itself

Abstract

backgroundChronic lateral ankle instability (CLAI) often arises from inadequately managed injuries to the lateral collateral ligaments, potentially leading to osteochondral lesions of the talus (OLT) and subsequent osteoarthritis. Hepple Stage V OLT, characterized by subchondral cysts, presents a significant therapeutic challenge. This study aimed to evaluate the efficacy of arthroscopic anterior talofibular ligament (ATFL) repair combined with retrograde drilling and allograft bone grafting in patients with CLAI and Hepple Stage V OLT with an intact talar articular surface.

methodsThis retrospective, small-sample exploratory study included 12 patients (ten men; median age: 35 years) who underwent arthroscopic treatment (between January 2020 and December 2022) for chronic lateral ankle instability with subchondral cysts, specifically Hepple Stage V OLT cases with an intact talar articular surface, after failing non-surgical interventions. The ATFL was repaired using the all-inside Internal Brace (IB) augmentation with the arthroscopic modified Broström operation. Treatment for OLT involved simultaneous retrograde drilling and allograft bone grafting. The median follow-up duration was 24 months (range: 20-35 months). The improvement of postoperative ankle pain was assessed using the Visual Analogue Scale (VAS), and the improvement of ankle function was evaluated using the American Orthopedic Foot ༆ Ankle Society (AOFAS) score and Foot༆Ankle Outcome Score (FAOS). Radiographic assessments were conducted at a minimum of 12 months postoperatively.

resultsAll 12 patients (12 ankles; 100%) returned for clinical and radiological follow-up at an average of 24 months (20-35 months) postoperatively. Subjective improvement was reported after arthroscopic surgery. The median AOFAS score demonstrated a substantial improvement from 67 preoperatively (range: 58-70) to 94 at the final follow-up (range: 90-98), with P < 0.05. Similarly, The FAOS score improved from 65 preoperatively (range: 58-75) to 91 at the final follow-up (range: 89-97), with P < 0.05. Radiographic follow-up results indicated satisfactory healing of the ATFL and favorable bone ingrowth post-subchondral cyst bone grafting.

conclusionArthroscopic ATFL repair combined with retrograde drilling and allograft bone grafting yields favorable clinical and radiographic outcomes in patients with CLAI and Hepple Stage V OLT. This integrated approach addresses both ligament instability and subchondral cyst pathology, potentially delaying the progression of osteoarthritis.

Indexed as

Ankle JointArthroscopyBone TransplantationJoint InstabilityLateral Ligament, AnkleTalusAdultAllograftsChronic DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultAllograft bone graftingAnterior talofibular ligamentChronic lateral ankle instabilityOsteochondral lesions of the talusRetrograde drilling

Identifiers

PMID41063055
PMCPMC12505644

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.