ArticleBMC psychiatry2025
Assessing the relationship between suicidality and inflammatory biomarkers: C-reactive protein/albumin and neutrophil/albumin ratios in an inpatient setting.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Inflammatory Biomarkers in Acute Suicidal Behaviors.International journal of molecular sciences · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuicidality is a significant public health concern with multifactorial etiologies, including psychological, environmental, and biological factors. Emerging evidence suggests a strong association between inflammatory processes and suicidality. This study aims to investigate the relationship between suicidality and inflammatory biomarkers in psychiatric inpatients.
methodsThis retrospective cross-sectional study included female psychiatric inpatients aged 18-65 years admitted to the Psychiatry Department of Goztepe Prof. Dr. Suleyman Yalcin City Hospital between 2022 and 2024. Inflammatory biomarkers, including C-reactive protein (CRP), albumin, neutrophils, lymphocytes, monocytes, platelets, and red cell distribution width (RDW), mean platelet volume (MPV) were analyzed. Additionally, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), CRP-to-albumin ratio (CAR), and neutrophil-to-albumin ratio (NAR) were calculated.
resultsThe analysis revealed no statistically significant differences between patients with suicidality (including both suicide ideation and history of suicide attempts) and the non-suicidality group in terms of MPV, RDW, NLR, MLR, PLR, CAR or NAR values, with all parameters showing p > 0.05.
conclusionsThe absence of statistically significant differences in inflammatory markers suggests that these biomarkers may not be robust indicators of suicidality in this sample. Further research with larger, more diverse populations is warranted to clarify the potential role of inflammation in suicidality.
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