Evidence map›Paper›PMID 41063014›Full record

ArticleBMC public health2025

Longitudinally investigating patterns of maternal psychological distress in a South African birth cohort.

Rae MacGinty, Nadia Hoffman, Nastassja Koen, Heather J Zar, Dan J Stein, Jennifer Pellowski

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rae MacGintyDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. raemacginty@gmail.com.
Nadia HoffmanDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Nastassja KoenDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Heather J ZarDepartment of Pediatrics and Child Health, Red Cross War Memorial Children's Hospital and South African Medical Research Council Unit On Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.
Dan J SteinDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Jennifer PellowskiDivision of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.

Funding

Early life determinants of cardiometabolic health from birth to adolescence amongst HIV-exposed and unexposed South African childrenR01HD108048 · NICHD · HARTFORD HOSPITAL · PI Angela Bengtson, Jennifer Ann Pellowski · 2022 to 2026
$2.8M
NICHD NIH HHS R01 HD108048NIH HHS R01HD108048
6 · The paper itself

Abstract

backgroundPsychological distress, a broad construct that encompasses of a range of emotional difficulties—including depression and anxiety—is prevalent during pregnancy and postnatally with up to 25% of women experiencing psychological distress globally. However, this is mostly described in high income countries (HIC), with little data from low- and middle-income countries (LMICs). The aim of this study was to describe and determine latent trajectory classes of maternal psychological distress from pregnancy through five years postpartum in a LMIC setting.

methodsData were used from women enrolled in the Drakenstein Child Health Study (DCHS), a birth cohort in South Africa. Women who had completed the Self-Report Questionnaire-20 items (SRQ-20) at two or more timepoints from pregnancy to 5 years postpartum, were included in the analysis. Latent class mixed modelling (LCMM) was used to generate latent trajectory classes of maternal psychological distress. Predictors, including trauma exposure, socio-economic indicators, substance use and pregnancy complications, of the latent classes were investigated using multinomial logistic regression.

resultsIn 973 women, four trajectory classes of maternal psychological distress were derived from pregnancy through 5 years postpartum, 1) persistent psychological distress symptoms, 2) antenatal symptoms only, 3) late postnatal onset of symptoms (post perinatal stage) and 4) low symptoms of psychological distress. Predictors of the persistent symptom class included early and recent trauma exposure, smoking during pregnancy, and gestational diabetes, whereas partner support was protective. Trauma exposure prior or during pregnancy was a predictor for the antenatal symptom class, while postnatal trauma exposure was associated with the late onset symptom class.

conclusionTrajectories and predictors of maternal psychological distress were found to be similar to those seen in depression only and in HIC, which suggests there could be a degree of universality with regards to predictors of psychological distress. Trauma experienced by women was found to be a critical risk factor for psychological distress, as was maternal smoking or lack of partner support. There is an urgent need for social transformation surrounding gender-based violence and prevention and smoking cessation programs targeting women of child bearing age.

Indexed as

MothersPregnancy ComplicationsPsychological DistressStress, PsychologicalAdultBirth CohortFemaleHumansLongitudinal StudiesPregnancySouth AfricaYoung AdultAnxietyDepressionLongitudinalLow and middle incomeMaternal psychological distress

Identifiers

PMID41063014
PMCPMC12505592

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.