ArticleBMC pregnancy and childbirth2025
The relationship between fetal tissue chromosomal karyotype and clinical characteristics in patients with spontaneous abortion: a retrospective study.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Caring for Early Pregnancy, Empowering Healthy Beginnings: Strengthening the Health Foundation of Youth Fertility in China on World Population Day 2026.China CDC weekly · 2026Article
- Transcervical, Transabdominal and Transvaginal Chorionic Villus Sampling for Prenatal Diagnosis in Zagreb, Croatia: A Prospective Single-Operator Study on 5500 Cases.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundAbnormal fetal tissue chromosome karyotypes are one of the important pathogenic factors for spontaneous abortion (SA). To analyze the characteristics of fetal tissue chromosomal karyotype in 778 women with a history of SA and its relationship with clinical features.
methodsA retrospective study collected maternal age, body mass index (BMI), gestational weeks at miscarriage, the number of previous pregnancy losses and fetal tissue karyotypes CNV-seq data of 778 SA couples from Lanzhou University Second Hospital from October 2019 to December 2023, and described the characteristics of fetal tissue chromosomal karyotype and its relationship with clinical features.
resultsIn our study, 432 patients (55.53% of total) had abnormal fetal tissue chromosomal karyotypes, with the highest incidence being trisomy syndrome (46.99%, 203/432). Advanced maternal age (> 35 years), early pregnancy (< 12 weeks), and a history of less than four previous pregnancy losses were all identified as risk factors for fetal tissue chromosomal abnormalities.
conclusionThe results of this study indicate that fetal tissue chromosomal abnormalities are the primary factor leading to SA. Additionally, advanced maternal age (> 35years), early pregnancy (< 12 weeks), and the fewer number of previous pregnancy losses (≤ 4 times) are associated with a higher risk of fetal tissue chromosomal abnormalities following miscarriage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.