Observational studyBMC pregnancy and childbirth2025
Association of preconception cannabis use frequency with cannabis use during early pregnancy.
Observational study in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Innovative Methods for Prenatal Cannabis Exposure: Vapor Inhalation Chamber and Metabolite Quantification in Prairie Voles and Rats.Developmental psychobiology · 2026Article
- "It Wasn't Like I Was Trying to Run to Weed Right Away, I Wanted Other Options": A Qualitative Study of Prenatal Healthcare Experiences Among Latina Birthing People Using Cannabis in California.Cannabis (Albuquerque, N.M.) · 2026Article
- Modes of Preconception Cannabis Use and Prevalence of Cannabis Use Disorder.Cannabis (Albuquerque, N.M.) · 2026Article
- Motivation to Quit Using Cannabis Was Associated with Lower Cannabis Use Among Pregnant Women at Risk for Sexually Transmitted Infections.Women's health reports (New Rochelle, N.Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundCannabis use during pregnancy is increasingly common and is associated with adverse health outcomes for pregnant individuals and their offspring. Identifying preconception factors that are associated with prenatal cannabis use is critical to inform early prevention and intervention. This study tested whether frequency of preconception cannabis use was associated with cannabis use during early pregnancy using data from a large healthcare system with universal screening for cannabis use.
methodsThis observational study included pregnant individuals in Kaiser Permanente Northern California (KPNC) who self-reported any cannabis use (daily, weekly, or monthly or less) during the year before pregnancy from 2011 to 2022 (excluding 2020). Prenatal cannabis use was based on self-report and/or a positive toxicology test during the first trimester of pregnancy at entrance to prenatal care (at ~ 8 weeks gestation). Modified Poisson models were fit to assess associations between frequency of preconception cannabis use and prenatal cannabis use, adjusting for covariates.
resultsThe sample of 40,806 pregnancies from 36,622 unique individuals who self-reported any preconception cannabis use was 65.7% non-White; 27.6% were aged < 25 years. Nearly half (45.1%) screened positive for prenatal use, including 23.7% by self-report and 36.6% by positive toxicology test. Compared to monthly or less preconception cannabis use, daily use (adjusted prevalence ratio [aPR] = 2.66, 95% CI 2.59-2.73) or weekly use (aPR = 1.99, 95% CI 1.93-2.05) was associated with greater risk of prenatal cannabis use. Results were similar when prenatal cannabis use was based on self-report only or on toxicology testing only.
conclusionsGreater frequency of preconception cannabis use was associated with substantially increased risk of prenatal cannabis use. Findings reinforce the need for early harm prevention efforts focused on reducing the frequency of cannabis use among women of reproductive age, including screening, education, and early linkage to intervention.
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