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ArticleClinical oral investigations2025

Associations among self-reported oral health and intrinsic capacity domains in U.S. older adults: analysis from NHANES 2009-2014.

Vittorio Dibello, Silvano Quarto, Frank Lobbezoo, Karl G H Parisius, Madia Lozupone, Filippo Santarcangelo, Claudia Chiapparino, Antonio Daniele, Antonio Dibello, Vincenzo Solfrizzi and 1 more

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Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Vittorio DibelloDepartment of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. vittoriodibello1@gmail.com.ORCID 0000-0002-9880-0481
Silvano Quarto"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy.
Frank LobbezooDepartment of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Karl G H ParisiusDepartment of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Madia LozuponeDepartment of Translational Biomedicine and Neuroscience "DiBrain", University of Bari Aldo Moro, Bari, Italy.
Filippo SantarcangeloRey Juan Carlos University, Móstoles, Community of Madrid, Spain.
Claudia Chiapparino"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy.
Antonio DanieleDepartment of Neuroscience, Catholic University of Sacred Heart, Rome, Italy.
Antonio Dibello"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy.
Vincenzo Solfrizzi"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy.
Francesco Panza"Cesare Frugoni" Internal and Geriatric Medicine and Memory Unit, University of Bari "Aldo Moro", Bari, Italy. f_panza@hotmail.com.ORCID 0000-0002-7220-0656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe World Health Organization suggested a framework for intrinsic capacity (IC), a construct central to healthy aging, emphasizing five domains: cognition, vitality, locomotion, sensory function, and psychological well-being. Although oral health may influence these domains, it remains underexplored within the IC model. The present study was the first to comprehensively examine the associations among self-reported oral health and IC domains.

methodsWe analyzed data from 845 adults aged ≥ 60 years from the 2009-2014 National Health and Nutrition Examination Survey (NHANES), representing approximately 9.10 million non-institutionalized U.S. individuals aged ≥ 60 years. Self-reported oral health indicators included symptoms, treatment history, and hygiene behaviors. IC domains were approximated using conceptually aligned variables available in NHANES.

resultsPerceived gum disease and reported bone loss were inversely associated with unintentional weight loss (vitality) [odds ratio (OR) = 0.54; 95% confidence interval (CI):0.30-0.96 and OR = 0.56; 95%CI:0.35-0.90, respectively]. Regular flossing and visible tooth abnormalities were linked to lower (OR = 0.59; 95% CI:0.35-0.98) and increased risk of impaired locomotion (OR = 2.38; 95% CI:1.19-4.76), respectively. Reporting teeth becoming loose without injury, visible tooth abnormalities, and regular flossing were associated with cognitive impairment, but not in fully-adjusted models. No significant associations were observed for mouthwash use or having ever received treatment for gum disease.

conclusionSelf-reported oral health indicators were associated with several IC domains in older adults. CLINICAL RELEVANCE: These findings highlighted oral health as a relevant factor in functional aging and supported its inclusion in comprehensive assessments aimed at promoting autonomy and well-being in later life.

Indexed as

Oral HealthSelf ReportAgedAged, 80 and overFemaleHumansMaleMiddle AgedNutrition SurveysOral HygieneUnited StatesDepressive symptomsIntrinsic capacityLocomotionOral healthVitalityWeight loss

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.