A naturalistic examination of the effects of chronic and acute cannabis use on cognition and perceived symptoms of attention-deficit/hyperactivity disorder.

Amanda M Stueber, Emily M LaFrance, Robyn S Herbert, Carrie Cuttler

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Article in Psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Amanda M StueberDepartment of Psychology, Washington State University, PO Box 644820, Pullman, WA, 99164-4820, USA.

Emily M LaFranceDepartment of Psychology, Washington State University, PO Box 644820, Pullman, WA, 99164-4820, USA.

Robyn S HerbertDepartment of Psychology, Washington State University, PO Box 644820, Pullman, WA, 99164-4820, USA.

Carrie CuttlerDepartment of Psychology, Washington State University, PO Box 644820, Pullman, WA, 99164-4820, USA. carrie.cuttler@wsu.edu.ORCID http://orcid.org/0000-0002-5890-2985

Funding

Washington State University Alcohol and Drug Abuse Research Program Washington State University Alcohol and Drug Abuse Research ProgramWashington State University Dedicated Marijuana Account Washington State University Dedicated Marijuana Account

6 · The paper itself

Abstract

rationalePeople with attention-deficit/hyperactivity disorder (ADHD) are more likely to use cannabis. However, the effects of chronic and acute cannabis use on people with ADHD remain unclear.

methods104 adults (26 cannabis users with ADHD, 26 non-users with ADHD, 26 cannabis users without ADHD, and 26 non-users without ADHD) were recruited to assess the impacts of cannabis use on perceived ADHD symptoms and cognition, through a repeated-measures, quasi-experimental study. In session one, participants completed a battery of cognitive tests and provided ADHD symptom (impulsivity, hyperactivity, inattention) and affect (irritability, anxiety, mood) ratings. In session two, cannabis users were observed using their own cannabis product while non-users remained sober, prior to completing the same battery of cognitive tests and symptom ratings.

resultsChronic cannabis users with ADHD self-reported less severe sluggish cognitive tempo than non-users with ADHD. Nevertheless, chronic cannabis users with (and without) ADHD demonstrated worse performance on two objective tests of cognition. Intoxicated cannabis users with ADHD self-reported reductions in impulsivity, irritability, and anxiety as well as enhanced mood, and demonstrated reductions in impulsive responding on two cognitive tests. Nevertheless, intoxicated cannabis users with (and without) ADHD demonstrated reductions in performance on five of the other cognitive outcomes.

conclusionThe present study provides limited evidence that acute cannabis intoxication may selectively reduce subjective and objective impulsivity in people with ADHD, while impairing several other aspects of cognition. In contrast, chronic cannabis use appears to reduce perceptions of sluggish cognitive tempo without producing any objective benefits to cognition.

Indexed as

Attention Deficit Disorder with HyperactivityCannabisCognitionMarijuana UseAdultAffectFemaleHumansImpulsive BehaviorMaleNeuropsychological TestsYoung AdultAffectAttentionAttention-deficit/hyperactivity disorderCannabisCognitionExecutive functionMemory

Identifiers

PMID41062851

DOI10.1007/s00213-025-06921-9

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.