Evidence map›Paper›PMID 41062802›Full record

Trial reportMolecular psychiatry2025

Gesture deficits in psychosis and the combination of group psychotherapy and transcranial magnetic stimulation: A randomized clinical trial.

Sebastian Walther, Lydia Maderthaner, Victoria Chapellier, Sofie von Känel, Daniel R Müller, Stephan Bohlhalter, Mischa Baer, Anastasia Pavlidou

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastian WaltherUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland. Walther_S5@ukw.de.ORCID http://orcid.org/0000-0003-4026-3561
Lydia MaderthanerUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.
Victoria ChapellierUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.
Sofie von KänelUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4875-7486
Daniel R MüllerUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.
Stephan BohlhalterDepartment of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Mischa BaerUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.
Anastasia PavlidouUniversity Hospital of Psychiatry and Psychotherapy Bern, Translational Research Center, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-5590-3456

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 184717
6 · The paper itself

Abstract

Hand gesture deficits are common in schizophrenia predicting poor social functioning with no treatment currently available. We used 10-sessions of repetitive transcranial magnetic stimulation (rTMS; 2-weeks) over the right inferior parietal lobe (IPL) in combination with 16-sessions of social cognitive remediation group therapy (SCRT; 8-weeks) to examine improvements in hand gesture performance in schizophrenia. In this 3-arm, double-blind, randomized, sham-controlled trial, 89 patients were randomized and 73 received at least one session of rTMS/SCRT: 19 patients were allocated to the real rTMS + real SCRT treatment, 26 to the sham rTMS + real SCRT treatment, and 28 to sham SCRT treatment. Hand gesture performance along with socio-cognitive and functional assessments were examined at 2-weeks, 8-weeks, and 32-weeks follow-up. Of 73 patients analyzed, (57% male), 53 completed the intervention and week-8 assessments. At week-8 no difference in overall hand gesture performance accuracy was observed across treatments. However, at week-32 follow-up the real rTMS + real group SCRT treatment showed significant improvements in novel unlearned gestures (F

Indexed as

GesturesPsychotherapy, GroupPsychotic DisordersTranscranial Magnetic StimulationAdultCognitive RemediationCombined Modality TherapyDouble-Blind MethodFemaleHumansMaleMiddle AgedParietal LobeSchizophreniaTreatment Outcome

Identifiers

PMID41062802
PMCPMC12602348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.