Evidence map›Paper›PMID 41062783›Full record

ReviewCurrent osteoporosis reports2025

The Role of Osteoporosis in Spine Surgery and Current Management Strategies: A Review.

Jordan Bauer, Bryan Heard, Hardeep Singh, Scott Mallozzi, Isaac Moss

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current osteoporosis reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jordan BauerDepartment of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA.
Bryan HeardDepartment of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA.
Hardeep SinghDepartment of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA.
Scott MallozziDepartment of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA.
Isaac MossDepartment of Orthopaedic Surgery, University of Connecticut, 120 Dowling Way, Farmington, CT, 06030, USA. imoss@uchc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewOsteoporosis is a systemic skeletal disease that presents unique challenges in spine surgery due to decreased bone mass, poor bone quality, and increased risk of fractures. This review aims to synthesize current understanding of osteoporosis in the context of spinal procedures, emphasizing the pathophysiology, diagnostic challenges, perioperative considerations, and evolving management strategies. RECENT

findingsDespite high prevalence, osteoporosis remains underdiagnosed and undertreated in surgical candidates, with preoperative bone mineral density (BMD) screening often overlooked. Recent evidence underscores the importance of optimizing bone health preoperatively through pharmacologic therapies, which includes bisphosphonates, denosumab, and anabolic agents like teriparatide and romosozumab. Furthermore, surgical innovations such as cement augmentation and biomechanically optimized pedicle screw techniques are thoroughly discussed. New modalities, such as CT-based Hounsfield unit assessments and finite element analysis, offer improved preoperative evaluation of bone quality. Successful spine surgery outcomes in osteoporotic patients require a multidisciplinary approach that integrates early screening, targeted pharmacologic treatment, lifestyle modifications, and advanced surgical planning. Addressing osteoporosis comprehensively improves implant fixation, reduces complications like pseudoarthrosis and junctional failures, and enhances overall patient quality of life.

Indexed as

OsteoporosisOsteoporotic FracturesBone DensityBone Density Conservation AgentsDenosumabDiphosphonatesHumansSpinal FusionBone Density Conservation AgentsDenosumabDiphosphonatesFragility fractureOsteoporosisSpine

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.