Evidence map›Paper›PMID 41062760›Full record

ArticleSurgical endoscopy2026

Laparoscopic pancreatoduodenectomy and venous resection are safe in selected patients: a monocentric comparative study in 30 patients.

Elias Karam, Yannick Morel, Béatrice Aussilhou, Wei-Liang Loh, Mickaël Lesurtel, Alain Sauvanet, Safi Dokmak

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elias KaramDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Yannick MorelDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Béatrice AussilhouDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Wei-Liang LohDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Mickaël LesurtelDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Alain SauvanetDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Safi DokmakDepartment of Hepato-Bilio-Pancreatic Surgery and Liver Transplantation, APHP, Hôpital Beaujon, DMU DIGEST, APHP, 100 boulevard du Général Leclerc, 92110, Clichy, France. safi.dokmak@aphp.fr.ORCID 0000-0002-3335-4388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnsuring oncologic resections margins may involve venous resection (VR) during pancreatoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC). Data regarding laparoscopic VR surgical outcomes in comparison with the open approach are lacking. Hence, we sought to compare the outcomes of laparoscopic PD (LPD) and open PD (OPD) with VR.

methodsWe retrospectively analyzed data from patients with resectable or borderline PDAC undergoing LPD or OPD with lateral or segmental portal/superior mesenteric vein resection in a high-volume center between 2012 and 2023.

resultsNinety-eight patients were included (30 LPD and 68 OPD). Patients in both groups had similar median age (62 vs 67, P = 0.166). Patients who underwent LPD had less neoadjuvant chemoradiotherapy (63% vs 91%, P = 0.003), but more lateral VR (83% vs 63%, P = 0.058), more reconstructions with a peritoneal patch (43% versus 19%, P = 0.024), longer median clamping time (28 vs 15 min, P < 0.001) and operative time (383 vs 255 min, P < 0.001). Patients in the LPD group showed similar rate of Clavien-Dindo morbidity > II (27% vs 16%, P = 0.271), 90-day mortality (3% vs 2%, P = 0.521), median length of stay (14 vs 14 days, P = 0.890), and R0 resection rate (73% vs 89%, P = 0.066) when compared to patients in the OPD group. At 6-month follow-up, venous patency rates between both groups was similar (76% vs 73%, P = 0.691).

conclusionLPD and OPD with VR have similar short-term and oncologic outcomes for patients with resectable or borderline PDAC.

Indexed as

Carcinoma, Pancreatic DuctalLaparoscopyMesenteric VeinsPancreatic NeoplasmsPancreaticoduodenectomyPortal VeinAgedFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomeLaparoscopicMinimally invasivePancreatic cancerPancreatoduodenectomyVascular resectionVenous resection

Identifiers

PMID41062760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.