Evidence map›Paper›PMID 41062733›Full record

ArticleWorld journal of urology2025

Application of perineal pedicled tubular flap in the treatment of complex bulbomembranous urethral strictures.

Chao Deng, Wenzhuo Fang, Lujie Song, Yuemin Xu, Yinglong Sa, Hang Guo, Tao Liang, Qiang Fu

Abstract read
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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chao Deng *Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Wenzhuo Fang *Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Lujie SongDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yuemin XuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Yinglong SaDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Hang GuoDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Tao LiangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China.
Qiang FuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University, Shanghai, 200233, China. jamesqfu@126.com.

Funding

National Scientific Foundation of China 82370684, 82170694Shanghai "Science and Technology Innovation Action Plan" Medical Innovation Research Program 22Y11905000the 2022 Shanghai Leading Talent Training Program 026the Interdisciplinary Program of Shanghai Jiao Tong University YG2022ZD020the Natural Science Foundation of Shanghai 20ZR1442100
6 · The paper itself

Abstract

objectiveTo evaluate the feasibility and clinical effectiveness of urethroplasty using a perineum-based scrotal flap (PBSF) for complex bulbomembranous urethral strictures (BMUS ≥ 5 cm with severe scarring).

methodsWe retrospectively analyzed 26 patients with complex BMUS treated at Shanghai Sixth People's Hospital between January 2015 and June 2024. The median stricture length was 7.0 cm (IQR: 5.8-8.5). The preoperative maximum urinary flow rate (Qmax) was 2.8 ± 2.5 ml/s. Standard posterior urethroplasty steps were performed, and when tension-free anastomosis was not possible, a full-thickness pedicled perineal flap was harvested and tubularized to bridge the defect. A silicone catheter was left in place for 4 weeks. All patients underwent uroflowmetry, retrograde urethrography (RUG) and voiding cystourethrography (VCUG) to determine the stricture length, location and recurrence. Erectile function was assessed using the International Index of Erectile Function-5 (IIEF-5).

resultsPostoperative Qmax significantly improved to 18.1 ± 11.3 ml/s (P < 0.001). Nineteen patients (73.1%) achieved both anatomical and functional success. Seven patients experienced Clavien-Dindo grade III complications (26.9%). Anastomotic strictures (4 patients, 15.4%): two treated with internal urethrotomy, two underwent cystostomy). Hair growth with stone formation (2 patients, 7.7%): Both experienced recurrence after endoscopic lithotripsy. Urethral skin fistula (1 patient, 3.8%): successfully managed with re-urethroplasty. No significant change in erectile function was observed (P = 0.396).

conclusionPBSF urethroplasty provides well-vascularized tissue, flexible dimensions, and reliable tubularization. It is a viable option for long-segment BMUS, especially in patients with hairless perineal skin and when end-to-end anastomosis is not feasible.

Indexed as

Surgical FlapsUrethraUrethral StrictureUrologic Surgical Procedures, MaleAdultAgedFeasibility StudiesHumansMaleMiddle AgedPerineumRetrospective StudiesScrotumTreatment OutcomeBulbomembranous urethraPedicled flapUrethral strictureUrethroplasty

Identifiers

PMID41062733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.