ArticleNature immunology2025
Temporal and context-dependent requirements for the transcription factor Foxp3 expression in regulatory T cells.
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Stemness-associated MEF-derived extruded nanovesicles cooperate withNanoscale advances · 2026Article
- Multimerizing transcription factors FOXP3 and AIRE as chromatin architectural regulators.Nature immunology · 2026Review
- FOXP-stabilization of thebioRxiv : the preprint server for biology · 2026Article
- Article
- Review
- Review
- Beyond Foxp3 and TSDR: a dual epigenetic lock framework for treg stability and plasticity.Frontiers in immunology · 2026Review
- Regulatory T cells in autoimmune diseases: biological mechanisms, clinical translation, and translational challenges.Frontiers in immunology · 2026Review
- Immunosuppressive cells as barriers to cancer therapy: mechanisms and emerging solutions.Frontiers in immunology · 2026Review
- Immune microenvironment dynamics in pregnant patients with concomitant autoimmune diseases: mechanisms, challenges, and clinical significance.Military Medical Research · 2026Review
- [Targeting Regulatory T Cells to Remodel Peripheral Immune Tolerance: Research Advances and Future Directions].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Review
- [Guardians of Immune Tolerance: Regulatory T Cells].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Review
Corrections and comments
- Update of
Authors and funding
14 authors.
Wei Hu *Howard Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. wei.hu.wh447@yale.edu.ORCID http://orcid.org/0000-0002-0392-6939
Gabriel A Dolsten *Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Eric Y Wang *Howard Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-6120-5136
Giorgi Beroshvili *Howard Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Zhong-Min WangHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Aazam P GhelaniHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lion F K UhlHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Regina Bou-PuertoHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-7546-3312
Xiao HuangHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anthony J MichaelsHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Beatrice E HoyosHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Wenjie JinDepartment of Immunobiology and Institute of Biomolecular Design and Discovery, Yale University, West Haven, CT, USA.ORCID http://orcid.org/0000-0002-7527-6357
Yuri PritykinLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. pritykin@princeton.edu.ORCID http://orcid.org/0000-0001-6589-981X
Alexander Y RudenskyHoward Hughes Medical Institute and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. rudenska@mskcc.org.ORCID http://orcid.org/0000-0003-1280-2898
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MWeill Cornell/Rockefeller/Sloan Kettering MST ProgramT32GM152349 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KATHARINE C HSU · 2024 to 2026
$6.6MSELF PEPTIDES BOUND TO MHC CLASS II IN T CELL SELECTIONR01AI034206 · NIAID · UNIVERSITY OF WASHINGTON · PI Alexander Y Rudensky · 1998 to 2026
$6.4MSelf Peptides Bound to MHC Class II In T Cell SelectionR37AI034206 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI RUDENSKY, ALEXANDER Y · 2009 to 2018
$4.8MRegulatory genomics of T cells in mouse and humanDP2AI171161 · NIAID · PRINCETON UNIVERSITY · PI Yury Pritykin · 2022 to 2026
$2.4MDivision of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) AI034206Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) DP2AI171161NCI NIH HHS P30 CA008748NIAID NIH HHS DP2 AI171161NIAID NIH HHS R01 AI034206NIAID NIH HHS R37 AI034206NIGMS NIH HHS T32 GM152349U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA008748
Abstract
Regulatory T (T
Indexed as
Forkhead Transcription FactorsT-Lymphocytes, RegulatoryAnimalsGene Expression RegulationMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicTranscriptomeForkhead Transcription FactorsFoxp3 protein, mouse
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.