Evidence map›Paper›PMID 41062583›Full record

ArticleScientific reports2025

Return to work and factors influencing recovery after endoscopic transsphenoidal surgery for hypothalamic and pituitary tumors.

Kohei Suzuki, Yoshiteru Nakano, Masahiro Inoue, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Junkoh Yamamoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kohei SuzukiDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan. s-kohei@clinc.uoeh-u.ac.jp.
Yoshiteru NakanoDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Masahiro InoueDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Koichiro SatoDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Shohei NagasakaDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Ryo MiyaokaDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Takeshi SaitoDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Junkoh YamamotoDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu, Fukuoka, 807-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the return-to-work (RTW) rates and associated factors following endoscopic transsphenoidal surgery (eTSS) among patients with pituitary and hypothalamic tumors in Japan. The primary research question aimed to determine the variables affecting early RTW post-surgery. A retrospective analysis was conducted on 44 preoperatively employed patients who underwent eTSS at a single center between April 2018 and January 2025. Clinical data, including demographics, tumor characteristics, comorbidities, and perioperative variables, were extracted from the medical records. The primary outcome was RTW within 3 months of surgery. Statistical analyses were performed using t-tests and Fisher's exact tests. The median time to RTW was 5 weeks, and the RTW rates were 38.6%, 69.5%, and 75.0% at 1, 3, and 6 months, respectively, with an overall RTW rate of 84.1%. Factors such as a prolonged length of hospital stay (LOS), mental disorders, and the absence of prior TSS were significantly linked to delayed RTW at 3 months. Mental disorders also tended to decrease RTW at 6 months. No significant associations were found between adequate hormone replacement and age, sex, tumor type, or endocrinological dysfunction. Patients receiving multidisciplinary support for RTW tended to experience longer recovery periods, possibly reflecting a greater need. In patients undergoing eTSS for pituitary region tumors, a history of mental disorders, prolonged LOS, and no history of prior TSS were key factors could be associated with delayed RTW. Early identification of these factors may facilitate tailored multidisciplinary RTW support strategies.

Indexed as

EndoscopyHypothalamic NeoplasmsNeurosurgical ProceduresPituitary NeoplasmsReturn to WorkAdultAgedFemaleHumansJapanLength of StayMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultCraniopharyngiomaEndoscopic transsphenoidal surgeryMultidisciplinary supportPituitary adenomaPituitary neuroendocrine tumorReturn to work

Identifiers

PMID41062583
PMCPMC12508165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.