Evidence map›Paper›PMID 41062452›Full record

ArticleNucleic acids research2026

SMART v10: three decades of the protein domain annotation resource.

Ivica Letunic, Peer Bork

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Review
  9. Article
  10. Genome-Wide Identification of NLP Family Genes in Cultivated Strawberry (International journal of molecular sciences · 2026
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  13. ZmTB1Plants (Basel, Switzerland) · 2026
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  18. Genome-Wide Identification of theInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ivica Letunicbiobyte solutions GmbH, Bothestr 142, 69126 Heidelberg, Germany.ORCID 0000-0003-3560-4288
Peer BorkEMBL, Meyerhofstrasse 1, 69117 Heidelberg, Germany.

Funding

EMBLFederal Ministry of Research, Technology and Space W-de.NBI-014MWK
6 · The paper itself

Abstract

SMART (Simple Modular Architecture Research Tool, https://smart.embl.de) is a web-based platform for identifying and annotating protein domains and analyzing domain architectures. SMART version 10 features manually curated models for over 1300 protein domains. Approaching its 30th anniversary, SMART's user interface has been redesigned from the ground up, leveraging modern web technologies to enhance intuitiveness and usability. SMART's "Genomic" mode, which annotates proteins from completely sequenced genomes was synchronized with the current release of STRING, and now includes 12 035 species, compared to 5090 in the previous release. Protein and domain annotation pages have been updated with new information sources. Integration with eggNOG provides links to 17.5 million orthologous groups for over 53 million proteins. Additionally, synchronization with the interactive Pathways Explorer version 3 incorporates updated KEGG pathway and orthologous group data, enabling direct visualization on four distinct pathway overview maps.

Indexed as

Databases, ProteinMolecular Sequence AnnotationProtein DomainsProteinsSoftwareAnimalsGenomicsHumansInternetUser-Computer InterfaceProteins

Identifiers

PMID41062452
PMCPMC12807790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.