Evidence map›Paper›PMID 41062271›Full record

ReviewPractical neurology2026

Retired contact sports athletes with cognitive concerns: promoting lifelong brain health.

Neil Graham, Martina Del Giovane, Jessica Hain, Erin Rooney, Karl Zimmerman, Ying Lee, Daniel Friedland, Thomas D Parker, Simon Fleminger, Maneesh C Patel and 2 more

Abstract readReview
In one paragraph

Review in Practical neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Neil GrahamBrain Sciences, Imperial College London, London, UK neil.graham@imperial.ac.uk.ORCID http://orcid.org/0000-0002-0183-3368
Martina Del GiovaneUK Dementia Research Institute Centre for Care Research and Technology, Imperial College London, London, England, UK.
Jessica HainBrain Sciences, Imperial College London, London, UK.
Erin RooneyBrain Sciences, Imperial College London, London, UK.
Karl ZimmermanBrain Sciences, Imperial College London, London, UK.
Ying LeeBrain Sciences, Imperial College London, London, UK.
Daniel FriedlandBrain Sciences, Imperial College London, London, UK.
Thomas D ParkerBrain Sciences, Imperial College London, London, UK.
Simon FlemingerImperial College Healthcare NHS Trust, London, UK.
Maneesh C PatelDepartment of Imaging, Imperial College Healthcare NHS Trust, London, UK.
Richard SylvesterAcute Stroke and Brain Injury Unit, National Hospital for Neurology and Neurosurgery, London, UK.
David SharpBrain Sciences, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in some cases, neurodegeneration. There may be a range of pathologies present after trauma exposure, including Alzheimer's disease and chronic traumatic encephalopathy. Currently, we have only limited understanding of specific clinical phenotypes for distinct types of post-traumatic dementia, nor are there in vivo tests for many of the pathologies. Informed by our experience running a midlife brain health clinic for retired elite contact sport athletes, we describe a practical framework for the workup of athletes with cognitive concerns, highlighting key clinical features, an approach to investigation including neuroimaging and advanced fluid biomarkers, symptomatic management strategies and research directions.

Indexed as

AthletesAthletic InjuriesBrainCognition DisordersRetirementHumansCLINICAL NEUROLOGYDEMENTIAHEAD INJURYTRAUMA, PSYCHOL SEQUE

Identifiers

PMID41062271
PMCPMC13018758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.