Evidence map›Paper›PMID 41061948›Full record

ArticleDevelopmental biology2026

Metabolites produced by agat+ cells support regeneration in the planarian Schmidtea mediterranea.

Aubrey M Kent, Carlos Guerrero-Hernández, Carolyn Brewster, Sean McKinney, Jason A Morrison, Mary C McKinney, Eric J Ross, Frederick G Mann, Blair W Benham-Pyle, Alejandro Sánchez Alvarado

Abstract read
In one paragraph

Article in Developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aubrey M KentStowers Institute for Medical Research, Kansas City, MO, USA.
Carlos Guerrero-HernándezStowers Institute for Medical Research, Kansas City, MO, USA.
Carolyn BrewsterStowers Institute for Medical Research, Kansas City, MO, USA.
Sean McKinneyStowers Institute for Medical Research, Kansas City, MO, USA.
Jason A MorrisonStowers Institute for Medical Research, Kansas City, MO, USA.
Mary C McKinneyStowers Institute for Medical Research, Kansas City, MO, USA.
Eric J RossStowers Institute for Medical Research, Kansas City, MO, USA.
Frederick G MannStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Institute for Medical Research, Kansas City, MO, USA.
Blair W Benham-PyleStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Institute for Medical Research, Kansas City, MO, USA; Stem Cells and Regenerative Medicine Center, Cell and Gene Therapy Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Alejandro Sánchez AlvaradoStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Institute for Medical Research, Kansas City, MO, USA. Electronic address: asa@stowers.org.

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
The molecular basis of planarian regenerationR37GM057260 · NIGMS · UNIVERSITY OF UTAH · PI SANCHEZ ALVARADO, ALEJANDRO · 2009 to 2018
$2.8M
NIGMS NIH HHS R01 GM129325NIGMS NIH HHS R37 GM057260
6 · The paper itself

Abstract

Planarians exhibit extraordinary regenerative abilities driven by pluripotent neoblasts, yet the roles of post-mitotic progenitor and differentiated cells in this process remain incompletely understood. Here, we investigate the function of agat

Indexed as

AmidinotransferasesHelminth ProteinsPlanariansRegenerationAnimalsCell DifferentiationRNA InterferenceStem CellsAmidinotransferasesHelminth ProteinsArginine glycine amidinotransferaseRegenerationStem cells

Identifiers

PMID41061948
PMCPMC12643051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.