Evidence map›Paper›PMID 41061692›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2026

Comparison of 90-day morbidity and mortality between ileal conduit and orthotopic neobladder following radical cystectomy in a large, multi-institutional database The Canadian CBCis experience.

Hanaa Fekak, Wassim Kassouf, Rodney H Breau, Adrian Fairey, Agnihotram V Ramanakumar, Camilla Tajzler, Eric Hyndman, Jasmir G Nayak, Jonathan Izawa, Bobby Shayegan and 8 more

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Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Recovery after cystectomy and urinary diversion: patient experiences and challenges.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Hanaa FekakDivision of Urology, Université de Montréal, Montreal, QC Canada.
Wassim KassoufDivision of Urology, McGill University Health Center, Montreal, QC, Canada.
Rodney H BreauOttawa Hospital Research Institute, Division of Urology, University of Ottawa, Ottawa, ON, Canada.
Adrian FaireyDivision of Urology, Cross Cancer Centre, Edmonton, AB, Canada.
Agnihotram V RamanakumarResearch Institute, McGill University, Montreal, QC, Canada.
Camilla TajzlerResearch Institute, McGill University, Montreal, QC, Canada.
Eric HyndmanDivision of Urology, Alberta Health Services, Calgary, AB, Canada.
Jasmir G NayakSection of Urology, University of Manitoba, Winnipeg, MB, Canada.
Jonathan IzawaDivision of Urology, Western University, London, ON, Canada.
Bobby ShayeganDivision of Urology, McMaster University, Hamilton, ON, Canada.
Girish S KulkarniDivision of Urology, University of Toronto, Toronto, ON, Canada.
Afsaneh EskandariDepartment of Surgical Oncology/Urology, University Health Network, Toronto, ON, Canada.
Michele LoddeDivision of Urology, Université Laval, Quebec City, QC, Canada.
Ricardo A RendonDepartment of Urology, Dalhousie University, Halifax, NS, Canada.
D Robert SiemensDepartment of Urology, Queen's University, Kingston, ON, Canada.
Claudio JeldresDivision of Urology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Peter C BlackDepartment of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
Jean-Baptiste LattoufDivision of Urology, Université de Montréal, Montreal, QC Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn patients undergoing radical cystectomy, ileal conduit (IC) urinary diversions are more frequently carried out than orthotopic neo-bladder reconstructions (ONB). Patients selected for IC likely have more comorbidities, advanced disease, and older age, with many being poor candidates for ONB; ONB often ends up being selected by younger and healthier patients. Differences in complications experienced by IC and ONB patients may be due to differences between patients or urinary diversions. To guide patient counseling and care, we aimed to assess 90-day complications and mortality for patients undergoing either procedure in a large, contemporary, Canadian cohort.

methodsPatient information was obtained from the Canadian Bladder Cancer information system (CBCis), encompassing 14 academic Canadian centers. Patients who underwent radical cystectomy between February 2015 and September 2023 were included. Ninety-day complications were analyzed according to the Clavien-Dindo severity scale. Perioperative parameters and 90-day mortality were compared between IC and ONB diversion. We used rank-sum and Chi-squared exact tests as exploratory statistics. Unconditional logistic regression was used to evaluate the association between IC and ONB complications.

resultsOf 2161 patients, 1799 (83%) received an IC and 362 (17%) an ONB. Patients were followed for a median of 235 days (interquartile range [IQR] 486). The median age was 69 years (IQR 14). The age-adjusted Charlson comorbidity index was significantly higher in the IC group (median [IQR] 5 [2] vs. 4 [2], p<0.001). The 90-day complication rate was 46% and the 90-day mortality rate was 4.3% for the entire cohort. On multivariable logistic regression, the risk of overall complications was significantly higher in the ONB than in the IC group (odds ratio 2.2, 95% confidence interval 1.7-2.8, p<0.001). Ninety-day mortality was 4.9% in the IC group and 0.82% in the ONB group.

conclusionsIn this multi-institutional cohort, patients with ONB had higher odds of perioperative complications; however, there was no difference in higher-severity complications between diversions.

Identifiers

PMID41061692
PMCPMC13680011

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.