Evidence map›Paper›PMID 41061663›Full record

ReviewAnnals of botany2026

The mechanism and application of the selenium hyperaccumulator Cardamine hupingshanensis: status and challenges.

Guangxuan Du, Yuhua Duan, Yilin Fu, Linxi Yuan, Zihua Zhang, Wenyao Shi, Yidan Wang, Yingxue Ma, Zhi-Qing Lin, Hua Zhang and 1 more

Abstract readReview
In one paragraph

Review in Annals of botany, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guangxuan DuKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Collaborative Innovation of Modern Crops and Food Crops in Jiangsu, Jiangsu Key Laboratory of Crop Genetics and Physiology, and College of Agriculture, Yangzhou University, Yangzhou 225009, China.
Yuhua DuanDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Yilin FuDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Linxi YuanDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.ORCID 0000-0002-1043-8933
Zihua ZhangDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Wenyao ShiDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Yidan WangDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Yingxue MaDepartment of Health and Environmental Sciences, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Zhi-Qing LinDepartment of Environmental Sciences and Department of Biological Sciences, Southern Illinois University - Edwardsville, Edwardsville, IL 62026, USA.
Hua ZhangState Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China.
Tao LiKey Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Collaborative Innovation of Modern Crops and Food Crops in Jiangsu, Jiangsu Key Laboratory of Crop Genetics and Physiology, and College of Agriculture, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-8958-1355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardamine hupingshanensis is a selenium (Se) hyperaccumulating plant discovered in 2008 in China. This comprehensive review summarizes the state-of-the-art progress on the molecular mechanisms underlying Se hyperaccumulation in C. hupingshanensis. The direct mechanisms encompass the key genes involved in the Se accumulation, localization and transformation processes in the plant. Homocysteine S-methyltransferase (HMT) and methionine S-methyltransferase (MMT) may contribute to Se hyperaccumulation in C. hupingshanensis, supported by the detection of selenolanthionine in the water extraction fraction, and selenocystine and selenomethylcysteine in the proteolytic hydrolysate fraction. Indirect mechanisms, such as structural adaptations, sequestration/transportation, sulphur conservation, oxidative stress control, protein degradation and interactions with rhizosphere/endophytic microbiota, may also contribute to its Se hyperaccumulation. This review also explores the applications of Se biofortification and phytoremediation, highlighting the potential of C. hupingshanensis in enhancing Se content in crops and remediating Se-contaminated environments. Further investigation is needed into the challenges related to C. hupingshanensis, focusing on the pathways and processes of Se accumulation and transport within the rhizosphere soil-plant-air system, comparative studies that have used a multi-omics strategy to delve deeper into the molecular mechanisms of Se hyperaccumulation under various Se speciation treatments, the role of core microbiota, potential applications in food processing and agriculture, and the synergistic remediation of Se and other heavy metal contaminants.

Indexed as

CardamineSeleniumBiodegradation, EnvironmentalSeleniumCardamine hupingshanensiscore microbiotahealth benefitsphytoremediationselenium hyperaccumulation mechanismselenium speciation

Identifiers

PMID41061663
PMCPMC13006976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.