Evidence map›Paper›PMID 41061057›Full record

ArticleScience advances2025

CRISPR/Cas9-germline editing of

Kouhei Oonuma, Reiko Kuroda, Takayuki Uchida, Si-Ming Zhang

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. To live or to die: competitive exclusion ofFrontiers in immunology · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kouhei OonumaFrontier Research Institute, Chubu University, Kasugai, Aichi 487-8501, Japan.ORCID 0000-0002-2418-0865
Reiko KurodaFrontier Research Institute, Chubu University, Kasugai, Aichi 487-8501, Japan.ORCID 0000-0002-0268-7729
Takayuki UchidaFrontier Research Institute, Chubu University, Kasugai, Aichi 487-8501, Japan.ORCID 0009-0002-2191-2351
Si-Ming ZhangCenter for Evolutionary and Theoretical Immunology, Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0003-4986-9711

Funding

Genetics and genomics of schistosome resistance in snailsR01AI170587 · NIAID · UNIVERSITY OF NEW MEXICO · PI ZHANG, SI-MING · 2022 to 2025
$2.8M
NIAID NIH HHS R01 AI170587
6 · The paper itself

Abstract

Human schistosomiasis remains one of the most devastating parasitic diseases worldwide, and the development of genetically modified vector snails has long been a goal in the field. Here, we report the successful creation of genetically modified

Indexed as

BiomphalariaCRISPR-Cas SystemsGene EditingSchistosomiasisAnimalsHumansSchistosoma mansoni

Identifiers

PMID41061057
PMCPMC12506961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.