Evidence map›Paper›PMID 41060892›Full record

Observational studyJBRA assisted reproduction2026

Efficiency of mild ovarian stimulation with letrozole co-treatment in expected low ovarian responders.

Alfredo Cortés-Vazquez, Ismael Perez-Bautista, J Andreas Mejicanos-Quiñonez, Hector R Salazar-Ochoa, M Carmen Peraza-Briones, J Daniel Moreno-García, Alfredo L Cortés-Algara

Abstract readObservational Study
In one paragraph

Observational study in JBRA assisted reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alfredo Cortés-VazquezReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Ismael Perez-BautistaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
J Andreas Mejicanos-QuiñonezReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Hector R Salazar-OchoaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
M Carmen Peraza-BrionesReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
J Daniel Moreno-GarcíaReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Alfredo L Cortés-AlgaraReproductive Endocrinology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOvarian stimulation (OS) is a critical step in assisted reproductive techniques (ART); it has been routinely adopted since it substantially increases the whole process efficiency. Our study aims to compare the efficiency of mild OS with letrozole co-treatment vs. conventional OS in expected low ovarian responders.

methodsA single-centre, observational, comparative, non-experimental and retrospective study using our database at the Reproductive Endocrinology Department at Centro Médico Nacional 20 de Noviembre in Mexico City was performed.

resultsWe compared the total rFSH dosage per oocyte, we noticed a statistically significant difference between groups, Group A 388.9 vs. Group B 667.2IU per retrieved oocyte (p<0.0002, 105 to 450 IU CI 95%), Comparing total rFSH dosage per follicle, we noticed a statistically significant difference among Group A 397.5 vs. Group B 590.2IU per follicle (p<0.014, 39.2 to 346.2 IU, CI 95%).

conclusionsIn expected poor ovarian responders, mild ovarian stimulation with letrozole co-treatment is much more efficient than conventional stimulation.

Indexed as

Aromatase InhibitorsLetrozoleNitrilesOvulation InductionTriazolesAdultFemaleHumansPregnancyRetrospective StudiesAromatase InhibitorsLetrozoleNitrilesTriazolesefficiencyletrozolemildovarianstimulation

Identifiers

PMID41060892
PMCPMC13059642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.