Evidence map›Paper›PMID 41060862›Full record

ArticleIEEE transactions on pattern analysis and machine intelligence2026

Unified Cross-Modal Medical Image Synthesis With Hierarchical Mixture of Product-of-Experts.

Reuben Dorent, Nazim Haouchine, Alexandra Golby, Sarah Frisken, Tina Kapur, William Wells

Abstract read
In one paragraph

Article in IEEE transactions on pattern analysis and machine intelligence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Reuben Dorent
Nazim Haouchine
Alexandra Golby
Sarah Frisken
Tina Kapur
William Wells

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLLAND, POLINA · 2012 to 2022
$20.9M
TRD 3 - Enabling Technologies for Intraprocedural GuidanceP41EB028741 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Nobuhiko Hata, CLARE M TEMPANY · 2021 to 2026
$10.7M
Ultrasound based neurosurgical navigation with uncertainty visualizationR01EB032387 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI FRISKEN, SARAH, GOLBY, ALEXANDRA J · 2022 to 2025
$2.0M
Continuous Compensation of Brain Shift during NeurosurgeryR01EB027134 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI FRISKEN, SARAH · 2018 to 2021
$1.8M
New Tools for Enhancing Cerebral Angiography: From Planning to NavigationK25EB035166 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Nazim Haouchine · 2024 to 2026
$375k
NIBIB NIH HHS K25 EB035166NIBIB NIH HHS P41 EB015902NIBIB NIH HHS P41 EB028741NIBIB NIH HHS R01 EB027134NIBIB NIH HHS R01 EB032387
6 · The paper itself

Abstract

We propose a deep mixture of multimodal hierarchical variational auto-encoders called MMHVAE that synthesizes missing images from observed images in different modalities. MMHVAE's design focuses on tackling four challenges: (i) creating a complex latent representation of multimodal data to generate high-resolution images; (ii) encouraging the variational distributions to estimate the missing information needed for cross-modal image synthesis; (iii) learning to fuse multimodal information in the context of missing data; (iv) leveraging dataset-level information to handle incomplete data sets at training time. Extensive experiments are performed on the challenging problem of pre-operative brain multi-parametric magnetic resonance and intra-operative ultrasound imaging.

Identifiers

PMID41060862
PMCPMC13092166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.