Evidence map›Paper›PMID 41060816›Full record

SynthesisEmerging microbes & infections2025

Monkeypox in South Asia: a systematic review.

Kinley Wangdi, Ripon Adhikary, Ziqi Liu, Sotiris Vardoulakis, Rosemary A McFarlane, Manas Kotepui, Wenbiao Hu, Apiporn T Suwannatrai, Tsheten Tsheten

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kinley WangdiHEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Bruce, Australia.ORCID 0000-0002-8857-2665
Ripon AdhikaryNational Centre for Epidemiology and Population Health, Australian National University, Acton, Australia.ORCID 0000-0002-5441-6146
Ziqi LiuNational Centre for Epidemiology and Population Health, Australian National University, Acton, Australia.
Sotiris VardoulakisHEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Bruce, Australia.
Rosemary A McFarlaneHEAL Global Research Centre, Health Research Institute, Faculty of Health, University of Canberra, Bruce, Australia.
Manas KotepuiMedical Technology, Faculty of Science, Nakhon Phanom University, Nakhon Phanom, Thailand.
Wenbiao HuSchool of Public Health and Social Work, Queensland University of Technology, Kelvin Grove, Australia.
Apiporn T SuwannatraiDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Tsheten TshetenNational Centre for Epidemiology and Population Health, Australian National University, Acton, Australia.ORCID 0000-0002-8071-5721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox (Mpox) has emerged as a significant public health concern globally and in South Asia. Therefore, this systematic review aimed to provide a synthesis of the epidemiological pattern, clinical features, disease severity, and mitigation strategies in the region. A systematic review was conducted across four databases including PubMed, Scopus, Web of Science, and Ovid from inception to August 2024. Out of 2,430 studies, only 19 met the inclusion criteria with 111 confirmed Mpox cases. Forty percent (44) of patients were males and 45.9% (51) did not specify their sex. Young to middle-aged adults were most affected, with rare cases in a neonate. Around two-thirds (73.0%, 81) of Mpox patients were from India, followed by Pakistan (16.2%, 18) and Nigeria (resident in India) (9.9%, 11). Sixty-eight percent (76) of Mpox patients reported recent travel, particularly to UAE (27%, 21) and Saudi Arabia (26.3%, 20). Common signs and symptoms among cases were skin lesion (92.8%, 103), fever (82.0%, 91), lymphadenopathy (65.8%, 73), muscle ache (27.0%, 30), and genital and perianal lesions (17.1%, 19). Co-infection with herpes simplex virus and varicella zoster virus led to difficulty in diagnosis. Nearly all the studies used polymerase chain reaction for diagnosis. Public health responses varied across countries, including enhanced surveillance, contact tracing, and awareness campaigns, but vaccine availability remained limited. Mpox in South Asia was largely linked to travel-related transmission and primarily affected younger adults. Strengthening surveillance systems, a syndemic approach, diagnostic capacity, and targeted interventions are crucial to controlling its spread.

Indexed as

Mpox, MonkeypoxAdultAsiaAsia, SouthernFemaleHumansIndiaMaleMiddle AgedMonkeypox virusPakistandisease severityepidemiologyMpoxpublic health responseSouth Asiatransmission

Identifiers

PMID41060816
PMCPMC12541925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.