Evidence map›Paper›PMID 41060812›Full record

ArticlePhysiological genomics2025

The transcriptomes of hypothalamic micropunches reveal sex differences in regulatory processes across hibernation in the Arctic ground squirrel.

Cole K Deal, M Hoshi Sugiura, Kelly L Drew, Cory T Williams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Cole K DealDepartment of Biology, Colorado State University, Fort Collins, Colorado, United States.ORCID 0000-0003-1677-2729
M Hoshi SugiuraCenter for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, United States.ORCID 0000-0002-4240-5722
Kelly L DrewCenter for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, United States.ORCID 0000-0002-2436-5720
Cory T WilliamsDepartment of Biology, Colorado State University, Fort Collins, Colorado, United States.ORCID 0000-0001-6484-0816

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
Renovation of LARS for Arctic Ground Squirrel BreedingP20GM130443 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI Kriya L Dunlap · 2019 to 2026
$16.4M
Colorado State University (CSU)HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM103395HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM130443NIGMS NIH HHS P20 GM103395NIGMS NIH HHS P20 GM130443
6 · The paper itself

Abstract

Seasonal life-history events, such as migration, hibernation, and reproduction, depend on coordinated physiological changes. In vertebrates, a conserved thyroid hormone-signaling pathway in the hypothalamus is known to trigger many of these seasonal transitions. However, the broader processes and regulators modulating seasonal physiology are poorly defined. Recent research in Arctic ground squirrels (AGS,

Indexed as

HibernationHypothalamusSciuridaeSex CharacteristicsTranscriptomeAnimalsArctic RegionsFemaleMaleSeasonshibernationhypothalamusphysiologytanycytestranscriptomics

Identifiers

PMID41060812
PMCPMC12679999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.